Identification
HMDB Protein ID CDBP01264
Secondary Accession Numbers Not Available
Name Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
Description Not Available
Synonyms
  1. 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta
  2. Diphosphoinositide kinase 2-beta
  3. PI(5)P 4-kinase type II beta
  4. PIP4KII-beta
  5. Phosphatidylinositol-5-phosphate 4-kinase type II beta
  6. PtdIns(5)P-4-kinase isoform 2-beta
Gene Name PIP4K2B
Protein Type Enzyme
Biological Properties
General Function Involved in phosphatidylinositol phosphate kinase activity
Specific Function Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate
GO Classification
Function
lipid kinase activity
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
phosphatidylinositol phosphate kinase activity
Process
metabolic process
phosphatidylinositol metabolic process
organophosphate metabolic process
phospholipid metabolic process
glycerophospholipid metabolic process
phosphoinositide metabolic process
Cellular Location
  1. Cell membrane
  2. Peripheral membrane protein
  3. Peripheral membrane protein
  4. Endoplasmic reticulum membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 17q12
SNPs PIP4K2B
Gene Sequence
>1251 bp
ATGTCGTCCAACTGCACCAGCACCACGGCGGTGGCGGTGGCGCCGCTCAGCGCCAGCAAG
ACCAAGACCAAGAAGAAGCATTTCGTGTGCCAGAAAGTGAAGCTATTCCGGGCCAGCGAG
CCGATCCTCAGCGTCCTGATGTGGGGGGTGAACCACACGATCAATGAGCTGAGCAATGTT
CCTGTTCCTGTCATGCTAATGCCAGATGACTTCAAAGCCTACAGCAAGATCAAGGTGGAC
AATCATCTCTTCAATAAGGAGAACCTGCCCAGCCGCTTTAAGTTTAAGGAGTATTGCCCC
ATGGTGTTCCGAAACCTTCGGGAGAGGTTTGGAATTGATGATCAGGATTACCAGAATTCA
GTGACGCGCAGCGCCCCCATCAACAGTGACAGCCAGGGTCGGTGTGGCACGCGTTTCCTC
ACCACCTACGACCGGCGCTTTGTCATCAAGACTGTGTCCAGCGAGGACGTGGCGGAGATG
CACAACATCTTAAAGAAATACCACCAGTTTATAGTGGAGTGTCATGGCAACACGCTTTTG
CCACAGTTCCTGGGCATGTACCGCCTGACCGTGGATGGTGTGGAAACCTACATGGTGGTT
ACCAGGAACGTGTTCAGCCATCGGCTCACTGTGCATCGCAAGTATGACCTCAAGGGTTCT
ACGGTTGCCAGAGAAGCGAGCGACAAGGAGAAGGCCAAGGACTTGCCAACATTCAAAGAC
AATGACTTCCTCAATGAAGGGCAGAAGCTGCATGTGGGAGAGGAGAGTAAAAAGAACTTC
CTGGAGAAACTGAAGCGGGACGTTGAGTTCTTGGCACAGCTGAAGATCATGGACTACAGC
CTGCTGGTGGGCATCCACGACGTGGACCGGGCAGAGCAGGAGGAGATGGAGGTGGAGGAG
CGGGCAGAGGACGAGGAGTGTGAGAATGATGGGGTGGGTGGCAACCTACTCTGCTCCTAT
GGCACACCTCCGGACAGCCCTGGCAACCTCCTCAGCTTTCCTCGGTTCTTTGGTCCTGGG
GAATTCGACCCCTCTGTTGACGTCTATGCCATGAAAAGCCATGAAAGTTCCCCCAAGAAG
GAGGTGTATTTCATGGCCATCATTGATATCCTCACGCCATACGATACAAAGAAGAAAGCT
GCACATGCTGCCAAAACGGTGAAACACGGGGCAGGGGCCGAGATCTCGACTGTGAACCCT
GAGCAGTACTCCAAACGCTTCAACGAGTTTATGTCCAACATCCTGACGTAG
Protein Properties
Number of Residues 416
Molecular Weight 47377.6
Theoretical pI 7.37
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV
PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS
VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL
PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD
NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE
RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK
EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT
GenBank ID Protein 4505819
UniProtKB/Swiss-Prot ID P78356
UniProtKB/Swiss-Prot Entry Name PI42B_HUMAN
PDB IDs
GenBank Gene ID NM_003559.4
GeneCard ID PIP4K2B
GenAtlas ID PIP4K2B
HGNC ID HGNC:8998
References
General References Not Available