| Identification |
|---|
| HMDB Protein ID
| CDBP01251 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serine/threonine-protein kinase Sgk2 |
| Description
| Not Available |
| Synonyms
|
- Serum/glucocorticoid-regulated kinase 2
|
| Gene Name
| SGK2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein serine/threonine kinase activity |
| Specific Function
| Involved in the activation of potassium channels |
| GO Classification
|
| Function |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.2 |
| SNPs
| SGK2 |
| Gene Sequence
|
>1284 bp
ATGCAGGGGTTGCTTACCTCGGGTAGGAAACCCTCAGGCGGTGGCAGGTGCACAGGTAGG
GGAGGATGGAGAGGGCAGTGGTGCCTGAAGCCCTGGATGGGCGGAGCTGACCCCCCAACA
CCAACTCTCTCATGCCTGCTCCTCCCTGTCCCCCCAGAGCTGCCTGATCATTGCTACAGA
ATGAACTCTAGCCCAGCTGGGACCCCAAGTCCACAGCCCTCCAGGGCCAATGGGAACATC
AACCTGGGGCCTTCAGCCAACCCAAATGCCCAGCCCACGGACTTCGACTTCCTCAAAGTC
ATCGGCAAAGGGAACTACGGGAAGGTCCTACTGGCCAAGCGCAAGTCTGATGGGGCGTTC
TATGCAGTGAAGGTACTACAGAAAAAGTCCATCTTAAAGAAGAAAGAGCAGAGCCACATC
ATGGCAGAGCGCAGTGTGCTTCTGAAGAACGTGCGGCACCCCTTCCTCGTGGGCCTGCGC
TACTCCTTCCAGACACCTGAGAAGCTCTACTTCGTGCTCGACTATGTCAACGGGGGAGAG
CTCTTCTTCCACCTGCAGCGGGAGCGCCGGTTCCTGGAGCCCCGGGCCAGGTTCTACGCT
GCTGAGGTGGCCAGCGCCATTGGCTACCTGCACTCCCTCAACATCATTTACAGGGATCTG
AAACCAGAGAACATTCTCTTGGACTGCCAGGGACACGTGGTGCTGACGGATTTTGGCCTC
TGCAAGGAAGGTGTAGAGCCTGAAGACACCACATCCACATTCTGTGGTACCCCTGAGTAC
TTGGCACCTGAAGTGCTTCGGAAAGAGCCTTATGATCGAGCAGTGGACTGGTGGTGCTTG
GGGGCAGTCCTCTACGAGATGCTCCATGGCCTGCCGCCCTTCTACAGCCAAGATGTATCC
CAGATGTATGAGAACATTCTGCACCAGCCGCTACAGATCCCCGGAGGCCGGACAGTGGCC
GCCTGTGACCTCCTGCAAAGCCTTCTCCACAAGGACCAGAGGCAGCGGCTGGGCTCCAAA
GCAGACTTTCTTGAGATTAAGAACCATGTATTCTTCAGCCCCATAAACTGGGATGACCTG
TACCACAAGAGGCTAACTCCACCCTTCAACCCAAATGTGACAGGACCTGCTGACTTGAAG
CATTTTGACCCAGAGTTCACCCAGGAAGCTGTGTCCAAGTCCATTGGCTGTACCCCTGAC
ACTGTGGCCAGCAGCTCTGGGGCCTCAAGTGCATTCCTGGGATTTTCTTATGCGCCAGAG
GATGATGACATCTTGGATTGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 427 |
| Molecular Weight
| 47603.9 |
| Theoretical pI
| 7.5 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serine/threonine-protein kinase Sgk2
MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYR
MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
YAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
LFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
CKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVS
QMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDL
YHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPE
DDDILDC
|
| External Links |
|---|
| GenBank ID Protein
| 20127541 |
| UniProtKB/Swiss-Prot ID
| Q9HBY8 |
| UniProtKB/Swiss-Prot Entry Name
| SGK2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_016276.3 |
| GeneCard ID
| SGK2 |
| GenAtlas ID
| SGK2 |
| HGNC ID
| HGNC:13900 |
| References |
|---|
| General References
| Not Available |