Identification |
HMDB Protein ID
| CDBP01228 |
Secondary Accession Numbers
| Not Available |
Name
| Protein ATP1B4 |
Description
| Not Available |
Synonyms
|
- X,K-ATPase subunit beta-m
- X/potassium-transporting ATPase subunit beta-m
|
Gene Name
| ATP1B4 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in sodium:potassium-exchanging ATPase activity |
Specific Function
| May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit |
GO Classification
|
Component |
membrane |
cell part |
Function |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
cation transmembrane transporter activity |
inorganic cation transmembrane transporter activity |
monovalent inorganic cation transmembrane transporter activity |
transporter activity |
potassium ion transmembrane transporter activity |
potassium-transporting atpase activity |
sodium:potassium-exchanging atpase activity |
Process |
nucleoside phosphate metabolic process |
nucleotide metabolic process |
sodium ion transport |
establishment of localization |
transport |
monovalent inorganic cation transport |
potassium ion transport |
purine nucleotide metabolic process |
ion transport |
purine nucleotide biosynthetic process |
atp biosynthetic process |
purine nucleoside triphosphate biosynthetic process |
cation transport |
purine ribonucleoside triphosphate biosynthetic process |
metabolic process |
nitrogen compound metabolic process |
cellular nitrogen compound metabolic process |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
nucleobase, nucleoside and nucleotide metabolic process |
|
Cellular Location
|
- Single-pass type II membrane protein
- Nucleus inner membrane
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| ATP1B4 |
Gene Sequence
|
>1074 bp
ATGAGAAGGCAACTCCGGTCCAGAAGGGCTCCATCCTTTCCTTACAGTTATCGCTACAGA
CTCGATGATCCGGATGAAGCGAACCAGAACTACTTAGCAGATGAAGAGGAGGAAGCAGAA
GAAGAGGCTCGGGTGACGGTGGTGCCCAAATCGGAGGAGGAGGAAGAAGAGGAGGAGAAA
GAAGAGGAGGAAGAGGAGGAAAAGGAGGAGGAAGAGGGTCAAGGTCAGCCAACAGGCAAT
GCCTGGTGGCAGAAATTGCAGATCATGAGTGAATACCTGTGGGATCCAGAGAGAAGGATG
TTTCTGGCCCGAACAGGTCAGAGTTGGAGCCTGATCTTACTCATTTACTTCTTCTTCTAT
GCCTCCTTGGCTGCTGTGATCACCCTCTGCATGTACACACTATTTCTGACCATCAGTCCC
TATATACCAACCTTCACGGAGCGGGTAAAGCCTCCTGGAGTTATGATCAGACCCTTCGCC
CATAGCCTTAACTTCAACTTCAACGTTTCTGAACCCGACACTTGGCAGCATTATGTGATT
AGCCTAAATGGCTTTCTCCAGGGTTATAATGACAGTCTTCAAGAGGAAATGAATGTAGAT
TGTCCCCCGGGGCAGTACTTCATCCAAGATGGCAATGAGGATGAGGACAAGAAGGCCTGC
CAATTTAAGCGCTCCTTCCTAAAGAACTGCTCTGGTCTGGAGGACCCAACTTTTGGATAC
TCTACTGGACAGCCCTGCATCCTTCTAAAGATGAACCGGATTGTAGGCTTTCGTCCTGAG
CTTGGAGATCCTGTGAAGGTTTCCTGCAAAGTTCAGAGAGGTGATGAAAATGACATCCGA
TCCATCAGTTACTACCCAGAGTCGGCTTCTTTTGACCTCCGCTACTACCCTTACTACGGC
AAACTGACTCACGTTAACTACACATCCCCCTTGGTGGCAATGCACTTTACAGACGTGGTG
AAGAACCAAGCAGTGCCTGTGCAGTGCCAACTGAAGGGCAAAGGCGTCATAAATGATGTC
ATCAATGATCGTTTTGTGGGCAGGGTAATCTTTACCCTGAACATAGAAACTTAA
|
Protein Properties |
Number of Residues
| 357 |
Molecular Weight
| 41597.4 |
Theoretical pI
| 4.4 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Protein ATP1B4
MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFY
ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
|
External Links |
GenBank ID Protein
| 5733590 |
UniProtKB/Swiss-Prot ID
| Q9UN42 |
UniProtKB/Swiss-Prot Entry Name
| AT1B4_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF158383 |
GeneCard ID
| ATP1B4 |
GenAtlas ID
| ATP1B4 |
HGNC ID
| HGNC:808 |
References |
General References
| Not Available |