Showing Protein Serine/threonine-protein kinase PRP4 homolog (CDBP01207)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP01207
Secondary Accession Numbers Not Available
Name Serine/threonine-protein kinase PRP4 homolog
Description Not Available
Synonyms
  1. PRP4 kinase
  2. PRP4 pre-mRNA-processing factor 4 homolog
Gene Name PRPF4B
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF
GO Classification
Function
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
Process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
phosphorus metabolic process
phosphate metabolic process
Cellular Location
  1. Nucleus
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p25.2
SNPs PRPF4B
Gene Sequence 
>3024 bp
ATGGCCGCCGCGGAGACCCAGTCGCTACGGGAGCAGCCAGAGATGGAAGATGCTAATTCT
GAAAAGAGTATAAATGAAGAAAATGGAGAAGTATCAGAAGACCAGTCTCAAAATAAGCAC
AGTCGTCACAAAAAAAAGAAGCATAAACACAGAAGTAAACATAAGAAACATAAACATTCC
TCAGAAGAAGACAAGGATAAAAAACATAAACATAAGCATAAACATAAGAAACACAAAAGA
AAAGAGATTATTGATGCTTCTGATAAAGAGGGTATGTCTCCAGCAAAAAGAACTAAACTT
GATGATTTAGCTTTGCTAGAAGACTTGGAAAAACAGAGAGCCTTGATTAAGGCCGAACTT
GATAATGAGTTAATGGAAGGAAAGGTCCAGTCTGGTATGGGGCTCATTTTGCAAGGTTAT
GAGTCTGGCTCTGAAGAAGAGGGGGAAATTCATGAAAAGGCAAGAAATGGAAATAGGTCT
AGTACTAGATCTTCAAGTACAAAGGGGAAACTTGAACTTGTGGACAATAAAATTACTACA
AAGAAACGAAGTAAAAGCAGATCCAAAGAACGGACTAGACATAGGTCTGATAAAAAGAAA
AGTAAGGGGGGTATTGAAATCGTTAAAGAGAAAACAACTAGGAGCAAGTCAAAGGAGAGG
AAAAAATCTAAAAGCCCATCCAAAAGAAGTAAGTCTCAAGATCAAGCAAGGAAATCAAAA
TCCCCTACCCTTAGAAGGCGATCTCAAGAGAAAATTGGTAAGGCCAGATCTCCTACTGAT
GATAAGGTTAAAATTGAAGATAAAAGTAAATCAAAAGATAGGAAAAAATCCCCAATTATA
AATGAAAGTAGAAGTCGCGATCGAGGTAAAAAATCCAGATCCCCAGTTGATTTAAGAGGT
AAATCCAAAGACAGAAGGTCACGGTCCAAAGAGAGAAAATCAAAACGGTCTGAAACTGAT
AAAGAAAAGAAGCCAATTAAATCTCCCTCTAAAGATGCTTCATCTGGGAAAGAAAATAGG
TCACCCAGCAGAAGACCTGGTCGTAGTCCTAAAAGAAGAAGTTTGTCTCCAAAACCACGT
GATAAATCAAGAAGAAGCAGGTCTCCACTTTTGAATGATAGAAGATCTAAGCAGAGCAAA
TCCCCCTCGCGGACACTGTCTCCTGGGAGAAGAGCCAAGAGCCGATCCTTAGAAAGAAAA
CGACGAGAACCAGAGAGGAGACGACTTTCTTCTCCAAGAACACGACCTCGAGATGATATC
CTCAGTAGACGTGAAAGATCAAAAGATGCCAGCCCCATCAATAGATGGTCTCCAACCCGA
AGAAGAAGTAGATCTCCCATTAGAAGGAGGTCTCGTTCCCCACTCAGACGTAGCAGGTCT
CCAAGAAGAAGAAGCAGATCTCCTCGGAGAAGGGACAGAGGTCGGAGGAGCAGATCACGC
TTGCGAAGGCGGTCTCGATCACGCGGTGGTCGTAGACGAAGGAGCAGAAGCAAAGTAAAG
GAAGATAAATTTAAAGGAAGTCTTTCTGAAGGAATGAAAGTTGAGCAGGAATCTTCGTCT
GATGATAACCTTGAAGACTTTGATGTAGAGGAAGAAGATGAAGAAGCCCTAATAGAACAG
AGAAGAATCCAAAGGCAGGCAATTGTTCAGAAATATAAATACCTTGCTGAAGATAGCAAC
ATGTCTGTGCCATCTGAACCAAGCAGCCCCCAGAGCAGTACGAGAACACGATCACCATCT
CCAGATGACATTCTGGAGCGAGTAGCTGCTGATGTTAAAGAGTATGAACGGGAAAATGTT
GATACATTTGAGGCCTCAGTGAAAGCCAAGCATAATCTAATGACAGTTGAACAGAATAAT
GGTTCATCTCAGAAGAAGTTGTTGGCACCTGATATGTTTACAGAATCTGATGATATGTTT
GCTGCGTATTTTGATAGTGCTCGTCTTCGGGCCGCTGGCATTGGAAAAGATTTCAAAGAG
AATCCCAACCTCAGAGATAACTGGACCGATGCAGAAGGCTATTATCGTGTGAACATAGGT
GAAGTCCTAGATAAACGTTACAATGTGTATGGCTACACTGGGCAAGGTGTATTCAGTAAT
GTTGTACGAGCCAGAGATAATGCAAGAGCCAACCAAGAAGTGGCTGTAAAGATCATCAGA
AACAATGAGCTCATGCAAAAGACTGGTTTAAAAGAATTAGAGTTCTTGAAAAAACTTAAT
GATGCTGATCCTGATGACAAATTTCATTGTCTGAGACTCTTCAGGCACTTCTATCACAAG
CAGCATCTTTGTCTGGTATTCGAGCCTCTCAGCATGAACTTACGAGAGGTGTTAAAAAAA
TATGGTAAAGATGTTGGTCTTCATATTAAAGCTGTAAGATCCTATAGTCAGCAGTTGTTC
CTGGCATTGAAACTCCTTAAAAGATGCAATATCCTACATGCAGATATCAAGCCAGACAAT
ATCCTGGTTAATGAATCCAAAACTATTTTAAAGCTTTGCGATTTTGGGTCGGCTTCACAT
GTTGCGGATAATGACATAACACCTTATCTTGTCAGTAGATTTTATCGTGCTCCTGAAATC
ATTATAGGTAAAAGCTATGACTATGGTATAGATATGTGGTCTGTAGGTTGCACCTTATAC
GAACTCTATACTGGAAAAATTTTATTCCCTGGCAAAACCAATAACCATATGCTGAAGCTT
GCAATGGATCTCAAAGGAAAGATGCCAAATAAGATGATTCGAAAAGGTGTGTTCAAAGAT
CAGCATTTTGATCAAAATCTCAACTTCATGTACATAGAAGTTGATAAAGTAACAGAGAGG
GAGAAAGTTACTGTTATGAGCACCATTAATCCAACTAAGGACCTGTTGGCTGACTTGATT
GGGTGCCAGAGACTTCCTGAAGACCAACGTAAGAAAGTACACCAGCTAAAGGACTTGTTG
GACCAGATTCTGATGTTGGACCCAGCTAAACGAATTAGCATCAACCAGGCCCTACAGCAC
GCCTTCATCCAGGAAAAAATTTAA
Protein Properties
Number of Residues 1007
Molecular Weight 116971.7
Theoretical pI 10.96
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Serine/threonine-protein kinase PRP4 homolog
MAAAETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHS
SEEDKDKKHKHKHKHKKHKRKEVIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAEL
DNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITT
KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSK
SPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRG
KSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPR
DKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDI
LSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSR
LRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQ
RRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENV
DTFEASVKAKHNLMTVEQNNGSSQKKLLAPDMFTESDDMFAAYFDSARLRAAGIGKDFKE
NPNLRDNWTDAEGYYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIR
NNELMQKTGLKELEFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKK
YGKDVGLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASH
VADNDITPYLVSRFYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKL
AMDLKGKMPNKMIRKGVFKDQHFDQNLNFMYIEVDKVTEREKVTVMSTINPTKDLLADLI
GCQRLPEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI
GenBank ID Protein 89276756
UniProtKB/Swiss-Prot ID Q13523
UniProtKB/Swiss-Prot Entry Name PRP4B_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003913.4
GeneCard ID PRPF4B
GenAtlas ID PRPF4B
HGNC ID HGNC:17346
References
General References Not Available