Identification |
HMDB Protein ID
| CDBP01206 |
Secondary Accession Numbers
| Not Available |
Name
| Inositol polyphosphate multikinase |
Description
| Not Available |
Synonyms
|
- Inositol 1,3,4,6-tetrakisphosphate 5-kinase
|
Gene Name
| IPMK |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in inositol trisphosphate 3-kinase activity |
Specific Function
| Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).
|
GO Classification
|
Biological Process |
neural tube formation |
inositol phosphate biosynthetic process |
Cellular Component |
nucleus |
Function |
inositol or phosphatidylinositol kinase activity |
inositol trisphosphate kinase activity |
inositol trisphosphate 3-kinase activity |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
Molecular Function |
ATP binding |
inositol-1,4,5-trisphosphate 3-kinase activity |
inositol tetrakisphosphate 3-kinase activity |
inositol-1,4,5-trisphosphate 6-kinase activity |
|
Cellular Location
|
- Nucleus
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Inositol Phosphate Metabolism | | | Inositol Metabolism | | |
|
Gene Properties |
Chromosome Location
| 10 |
Locus
| 10q21.1 |
SNPs
| IPMK |
Gene Sequence
|
>1251 bp
ATGGCAACAGAGCCACCATCCCCCCTCCGGGTCGAGGCGCCGGGCCCCCCAGAAATGCGG
ACCTCACCGGCGATCGAGTCCACCCCTGAGGGCACCCCGCAGCCGGCGGGCGGCAGACTC
CGCTTCCTCAACGGCTGCGTGCCCCTCTCGCATCAGGTGGCCGGGCACATGTACGGGAAG
GACAAAGTGGGTATACTGCAACATCCAGATGGCACAGTTTTGAAACAGTTACAACCACCT
CCAAGGGGCCCAAGAGAGCTGGAATTCTATAATATGGTTTATGCTGCTGACTGTTTTGAT
GGTGTTCTTCTAGAGCTACGAAAATATTTGCCAAAATATTATGGCATCTGGTCACCTCCC
ACTGCACCAAACGATTTATACCTAAAACTGGAAGATGTGACCCATAAATTTAATAAGCCC
TGTATAATGGATGTAAAGATAGGGCAAAAAAGCTATGATCCTTTTGCCTCATCTGAGAAG
ATTCAGCAACAGGTCAGCAAGTACCCATTAATGGAAGAGATTGGGTTCTTGGTGCTTGGC
ATGAGGGTTTATCATGTTCATTCCGATAGCTATGAGACAGAAAACCAGCATTACGGAAGA
AGCTTAACAAAAGAAACTATAAAGGATGGAGTCTCCAGATTTTTTCATAATGGGTACTGC
TTAAGAAAAGATGCTGTTGCTGCCAGTATTCAGAAGATTGAGAAAATTCTGCAGTGGTTT
GAAAACCAGAAGCAGCTTAATTTTTACGCAAGTTCATTACTCTTTGTTTATGAAGGTTCA
TCTCAGCCAACCACTACAAAATTGAATGACAGAACTTTGGCAGAAAAGTTTTTGTCCAAA
GGACAACTGTCAGACACAGAAGTACTAGAGTACAATAATAACTTTCATGTGTTAAGTTCC
ACAGCTAATGGAAAAATAGAGTCTTCAGTGGGCAAAAGCTTGTCCAAGATGTATGCGCGT
CACAGGAAAATATATACAAAAAAGCATCACAGTCAGACTTCATTGAAAGTTGAAAATCTG
GAGCAAGACAATGGGTGGAAAAGCATGTCACAGGAACATTTAAATGGAAATGTACTTTCC
CAACTGGAAAAAGTTTTCTACCATCTTCCCACTGGTTGCCAAGAGATTGCTGAAGTAGAA
GTGCGAATGATAGATTTTGCTCATGTGTTCCCTAGCAACACAATAGATGAGGGATATGTT
TATGGGCTAAAGCATTTAATTTCTGTACTTCGAAGTATTTTAGACAATTGA
|
Protein Properties |
Number of Residues
| 416 |
Molecular Weight
| 47221.455 |
Theoretical pI
| 7.634 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Inositol polyphosphate multikinase
MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK
DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP
TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG
MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF
ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS
TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS
QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN
|
External Links |
GenBank ID Protein
| 22532105 |
UniProtKB/Swiss-Prot ID
| Q8NFU5 |
UniProtKB/Swiss-Prot Entry Name
| IPMK_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF432853 |
GeneCard ID
| IPMK |
GenAtlas ID
| IPMK |
HGNC ID
| HGNC:20739 |
References |
General References
| Not Available |