1197
CDBP01196
1-phosphatidylinositol-3-phosphate 5-kinase
Q9Y2I7
FYV1_HUMAN
true
false
Enzyme
Homo_sapiens
PIKFYVE
2098
237134.1
6.67
Involved in protein binding
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol-3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol-3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes
["None"]
["None"]
NM_015040.3
121583483
PIKFYVE
Chromosome:2
2q34
PIKFYVE
HGNC:23785
true
2020-06-12T23:06:54Z
2020-07-28T02:26:34Z
0
1
0