Identification |
HMDB Protein ID
| CDBP01194 |
Secondary Accession Numbers
| Not Available |
Name
| V-type proton ATPase subunit G 2 |
Description
| Not Available |
Synonyms
|
- V-ATPase 13 kDa subunit 2
- V-ATPase subunit G 2
- Vacuolar proton pump subunit G 2
|
Gene Name
| ATP6V1G2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
Specific Function
| Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells |
GO Classification
|
Component |
proton-transporting two-sector atpase complex |
proton-transporting v-type atpase complex |
vacuolar proton-transporting v-type atpase complex |
macromolecular complex |
protein complex |
Function |
catalytic activity |
hydrolase activity |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
hydrolase activity, acting on acid anhydrides |
Process |
hydrogen transport |
proton transport |
establishment of localization |
transport |
|
Cellular Location
|
- Melanosome
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6p21.3 |
SNPs
| ATP6V1G2 |
Gene Sequence
|
>357 bp
ATGGCCAGTCAGTCCCAAGGTATCCAGCAGCTTCTGCAAGCTGAGAAGCGGGCAGCTGAG
AAGGTGGCAGATGCCAGAAAGAGGAAGGCCCGGCGACTGAAGCAGGCAAAGGAGGAGGCA
CAGATGGAGGTGGAGCAATACCGCAGAGAGCGAGAGCACGAATTCCAGAGCAAGCAGCAG
GCGGCCATGGGCTCCCAGGGGAACCTGTCTGCTGAGGTGGAGCAGGCTACAAGGCGCCAG
GTGCAGGGCATGCAGAGCTCCCAGCAGAGAAACCGAGAGCGTGTCCTGGCCCAGCTTCTT
GGCATGGTCTGCGACGTCAGGCCCCAGGTCCACCCCAACTACCGGATTTCTGCCTAG
|
Protein Properties |
Number of Residues
| 118 |
Molecular Weight
| 13604.3 |
Theoretical pI
| 10.9 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>V-type proton ATPase subunit G 2
MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQ
AAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA
|
External Links |
GenBank ID Protein
| 21623504 |
UniProtKB/Swiss-Prot ID
| O95670 |
UniProtKB/Swiss-Prot Entry Name
| VATG2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB063177 |
GeneCard ID
| ATP6V1G2 |
GenAtlas ID
| ATP6V1G2 |
HGNC ID
| HGNC:862 |
References |
General References
| Not Available |