Identification
HMDB Protein ID CDBP01194
Secondary Accession Numbers Not Available
Name V-type proton ATPase subunit G 2
Description Not Available
Synonyms
  1. V-ATPase 13 kDa subunit 2
  2. V-ATPase subunit G 2
  3. Vacuolar proton pump subunit G 2
Gene Name ATP6V1G2
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Specific Function Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells
GO Classification
Component
proton-transporting two-sector atpase complex
proton-transporting v-type atpase complex
vacuolar proton-transporting v-type atpase complex
macromolecular complex
protein complex
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
hydrolase activity, acting on acid anhydrides
Process
hydrogen transport
proton transport
establishment of localization
transport
Cellular Location
  1. Melanosome
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p21.3
SNPs ATP6V1G2
Gene Sequence
>357 bp
ATGGCCAGTCAGTCCCAAGGTATCCAGCAGCTTCTGCAAGCTGAGAAGCGGGCAGCTGAG
AAGGTGGCAGATGCCAGAAAGAGGAAGGCCCGGCGACTGAAGCAGGCAAAGGAGGAGGCA
CAGATGGAGGTGGAGCAATACCGCAGAGAGCGAGAGCACGAATTCCAGAGCAAGCAGCAG
GCGGCCATGGGCTCCCAGGGGAACCTGTCTGCTGAGGTGGAGCAGGCTACAAGGCGCCAG
GTGCAGGGCATGCAGAGCTCCCAGCAGAGAAACCGAGAGCGTGTCCTGGCCCAGCTTCTT
GGCATGGTCTGCGACGTCAGGCCCCAGGTCCACCCCAACTACCGGATTTCTGCCTAG
Protein Properties
Number of Residues 118
Molecular Weight 13604.3
Theoretical pI 10.9
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>V-type proton ATPase subunit G 2
MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQ
AAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA
GenBank ID Protein 21623504
UniProtKB/Swiss-Prot ID O95670
UniProtKB/Swiss-Prot Entry Name VATG2_HUMAN
PDB IDs Not Available
GenBank Gene ID AB063177
GeneCard ID ATP6V1G2
GenAtlas ID ATP6V1G2
HGNC ID HGNC:862
References
General References Not Available