Identification |
HMDB Protein ID
| CDBP01165 |
Secondary Accession Numbers
| Not Available |
Name
| Hormonally up-regulated neu tumor-associated kinase |
Description
| Not Available |
Synonyms
|
- B19
- Serine/threonine-protein kinase MAK-V
|
Gene Name
| HUNK |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein serine/threonine kinase activity |
Specific Function
| ATP + a protein = ADP + a phosphoprotein |
GO Classification
|
Function |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
protein kinase activity |
protein serine/threonine kinase activity |
Process |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
phosphorylation |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 21q22.1 |
SNPs
| HUNK |
Gene Sequence
|
>2145 bp
ATGCCGGCGGCGGCGGGGGACGGGCTCCTGGGGGAGCCGGCGGCGCCTGGGGGCGGCGGC
GGCGCGGAGGACGCGGCCAGGCCCGCGGCGGCCTGCGAGGGAAGTTTCCTGCCTGCCTGG
GTGAGCGGCGTGCCCCGCGAGCGGCTCCGCGACTTCCAGCACCACAAGCGCGTGGGCAAC
TACCTCATCGGCAGCAGGAAGCTGGGCGAGGGCTCCTTTGCCAAGGTGCGCGAGGGGCTG
CACGTGCTGACCGGGGAGAAGGTGGCCATAAAAGTCATTGATAAGAAGAGAGCCAAAAAG
GACACCTATGTCACCAAAAACCTGCGGCGAGAGGGTCAGATCCAGCAGATGATCCGCCAC
CCCAATATCACTCAGCTCCTTGATATTTTAGAAACGGAAAACAGCTACTACCTGGTCATG
GAGCTGTGCCCTGGGGGCAACCTGATGCACAAGATCTATGAGAAGAAGCGGCTGGAGGAG
TCCGAAGCCCGCAGATACATCCGACAGCTCATCTCTGCCGTAGAGCACCTGCACCGGGCC
GGGGTGGTCCACAGAGACTTGAAGATAGAGAATTTGCTACTAGATGAAGACAATAATATC
AAGCTGATTGACTTTGGTTTGAGCAACTGCGCAGGGATCCTGGGTTACTCGGATCCGTTC
AGCACACAGTGTGGCAGCCCTGCCTACGCTGCACCTGAACTGCTCGCCAGGAAGAAATAC
GGCCCCAAAATCGATGTCTGGTCCATAGGTGTGAACATGTATGCCATGTTGACCGGGACG
CTGCCTTTCACGGTGGAGCCTTTCAGCCTGAGGGCTTTGTACCAGAAGATGGTAGACAAA
GAAATGAACCCCCTCCCCACTCAGCTCTCCACAGGTGCCATCAGTTTCCTGCGCTCTCTC
CTGGAACCGGATCCTGTGAAGAGGCCAAATATTCAGCAGGCACTGGCGAATCGCTGGCTT
AATGAGAATTACACGGGCAAAGTGCCCTGTAATGTCACCTATCCCAACAGGATTTCTCTG
GAAGATCTGAGCCCGAGCGTCGTGCTGCACATGACCGAGAAGCTGGGTTACAAGAACAGC
GACGTGATCAACACTGTGCTCTCCAACCGCGCCTGCCACATCCTGGCCATCTACTTCCTC
TTAAACAAGAAACTGGAGCGCTATTTGTCAGGGAAATCTGACATCCAGGACAGCCTCTGC
TACAAGACCCGGCTCTACCAGATAGAAAAGTACAGGGCCCCCAAGGAGTCCTATGAGGCC
TCTCTGGACACCTGGACACGAGATCTTGAATTCCATGCCGTGCAGGATAAAAAGCCCAAA
GAACAAGAAAAAAGAGGGGATTTTCTTCATCGACCATTCTCCAAGAAGTTGGACAAGAAC
CTGCCCTCGCACAAACAGCCCTCAGGCTCGCTTATGACACAGATTCAGAACACCAAAGCC
CTCCTGAAGGACCGGAAGGCCTCCAAGTCCAGCTTCCCCGACAAAGATTCCTTTGGCTGC
CGCAATATTTTCCGCAAAACCTCAGATTCCAATTGTGTGGCTTCTTCTTCCATGGAGTTC
ATCCCCGTGCCACCGCCCAGGACCCCGAGGATTGTGAAGAAACCGGAGCCCCATCAGCCA
GGGCCCGGAAGCACTGGCATCCCCCACAAGGAAGACCCCCTGATGCTGGACATGGTGCGC
TCCTTCGAGTCTGTGGATCGCGACGACCACGTAGAAGTGCTGTCTCCCTCTCATCACTAC
AGGATTCTGAACTCCCCGGTCAGCTTGGCTCGCAGAAATTCCAGCGAGAGGACGCTGTCC
CCGGGTCTGCCATCCGGAAGCATGTCGCCTCTCCATACTCCTTTGCATCCAACTCTGGTC
TCTTTTGCTCACGAAGATAAGAACAGCCCCCCAAAAGAGGAGGGCCTGTGTTGCCCACCT
CCGGTTCCCAGCAATGGCCCCATGCAGCCTCTGGGGAGCCCCAATTGTGTGAAAAGCCGA
GGCCGGTTCCCTATGATGGGCATCGGACAGATGTTAAGGAAGCGCCATCAGAGTCTGCAG
CCATCTGCAGATAGGCCCCTGGAGGCCAGCCTGCCCCCACTGCAGCCCCTAGCCCCTGTG
AACCTTGCCTTTGACATGGCCGATGGGGTCAAGACCCAGTGCTAA
|
Protein Properties |
Number of Residues
| 714 |
Molecular Weight
| 79684.8 |
Theoretical pI
| 9.54 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Hormonally up-regulated neu tumor-associated kinase
MPAAAGDGLLGEPAAPGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGN
YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRH
PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA
GVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY
GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSL
LEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGYKNS
DVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSLCYKTRLYQIEKYRAPKESYEA
SLDTWTRDLEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSGSLMTQIQNTKA
LLKDRKASKSSFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPHQP
GPGSTGIPHKEDPLMLDMVRSFESVDRDDHVEVLSPSHHYRILNSPVSLARRNSSERTLS
PGLPSGSMSPLHTPLHPTLVSFAHEDKNSPPKEEGLCCPPPVPSNGPMQPLGSPNCVKSR
GRFPMMGIGQMLRKRHQSLQPSADRPLEASLPPLQPLAPVNLAFDMADGVKTQC
|
External Links |
GenBank ID Protein
| 6850973 |
UniProtKB/Swiss-Prot ID
| P57058 |
UniProtKB/Swiss-Prot Entry Name
| HUNK_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AJ271722 |
GeneCard ID
| HUNK |
GenAtlas ID
| HUNK |
HGNC ID
| HGNC:13326 |
References |
General References
| Not Available |