Cannabis Compound Database: Showing Protein Sodium/potassium-transporting ATPase subunit beta-2 (CDBP01150)

Identification Biological properties Gene properties Protein properties External links References XML Show 5 compounds

Identification

HMDB Protein ID

CDBP01150

Secondary Accession Numbers

Not Available

Name

Sodium/potassium-transporting ATPase subunit beta-2

Description

Not Available

Synonyms

Sodium/potassium-dependent ATPase subunit beta-2

Gene Name

ATP1B2

Protein Type

Enzyme

Biological Properties

General Function

Involved in sodium:potassium-exchanging ATPase activity

Specific Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known

GO Classification

Component
membrane
cell part
Function
potassium ion transmembrane transporter activity
potassium-transporting atpase activity
sodium:potassium-exchanging atpase activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
transporter activity
Process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
sodium ion transport
establishment of localization
transport
monovalent inorganic cation transport
potassium ion transport
purine nucleotide metabolic process
ion transport
purine nucleotide biosynthetic process
atp biosynthetic process
purine nucleoside triphosphate biosynthetic process
cation transport
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process

Cellular Location

Membrane
Single-pass type II membrane protein

Pathways

Name	SMPDB/Pathwhiz	KEGG
Kidney Function		Not Available
Glucose Transporter Defect (SGLT2)		Not Available
Hartnup Disorder		Not Available
Iminoglycinuria		Not Available
Lysinuric Protein Intolerance		Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17p13.1

SNPs

ATP1B2

Gene Sequence

>873 bp
ATGGTCATCCAGAAAGAGAAGAAGAGCTGCGGGCAGGTGGTTGAGGAGTGGAAGGAGTTC
GTGTGGAACCCGAGGACGCACCAGTTTATGGGCCGCACCGGGACCAGCTGGGCCTTTATC
CTCCTCTTCTACCTCGTTTTTTATGGGTTCCCCACCGCCATGTTCACCCTCACCATGTGG
GTGATGCTGCAGACTGTCTCCGACCATACCCCCAAGTACCAGGACCGACTGGCCACACCG
GGCTTGATGATTCGCCCCAAGACTGAGAACCTTGATGTCATTGTCAATGTCAGTGACACT
GAAAGCTGGGACCAGCATGTTCAGAAGCTCAACAAGTTCTTGGAGCCTTACAACGACTCT
ATGCAAGCCCAAAAGAATGATGTCTGCCGCCCTGGGCGCTATTACGAACAGCCAGATAAT
GGAGTCCTCAACTACCCCAAACTGGCCTGCCAATTCAACCGGACCCAGCTGGGCAACTGC
TCCGGCATTGGGGACTCCACCCACTATGGTTACAGCACTGGGCAGCCCTGTGTCTTCATC
AAGATGAACCGGGTCATCAACTTCTATGCAGGAGCAAACCAGAGCATGAATGTTACCTGT
GCTGGGAAGCGAGATGAAGATGCTGAGAATCTCGGCAACTTCGTCATGTTCCCCGCCAAC
GGCAACATCGACCTCATGTACTTCCCCTACTATGGCAAAAAGTTCCACGTGAACTACACA
CAGCCCCTGGTGGCTGTGAAGTTCCTGAATGTGACCCCCAACGTGGAGGTGAATGTAGAA
TGTCGCATCAACGCCGCCAACATCGCCACAGACGATGAGCGAGACAAGTTCGCCGGCCGC
GTGGCCTTCAAACTCCGCATCAACAAAACCTGA

Protein Properties

Number of Residues

290

Molecular Weight

33366.9

Theoretical pI

8.44

Pfam Domain Function

Na_K-ATPase (PF00287 )

Signals

["None"]

Transmembrane Regions

["40-67"]

Protein Sequence

>Sodium/potassium-transporting ATPase subunit beta-2
MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS
IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI
KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT
QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT

External Links

GenBank ID Protein

179245

UniProtKB/Swiss-Prot ID

P14415

UniProtKB/Swiss-Prot Entry Name

AT1B2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

M81181

GeneCard ID