| Identification |
|---|
| HMDB Protein ID
| CDBP01132 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ketohexokinase |
| Description
| Not Available |
| Synonyms
|
- Hepatic fructokinase
|
| Gene Name
| KHK |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| response to zinc ion |
| fructose catabolic process |
| response to fructose stimulus |
| response to insulin stimulus |
| response to glucose stimulus |
| response to sucrose stimulus |
| Cellular Component |
| cytosol |
| Molecular Function |
| ketohexokinase activity |
| ATP binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | fructose metabolism | Not Available | Not Available | | Fructose and mannose metabolism | Not Available |  | | Fructose and Mannose Degradation |    | | | Fructosuria |    | Not Available | | Fructose intolerance, hereditary |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| 2p23.3 |
| SNPs
| KHK |
| Gene Sequence
|
>897 bp
ATGGAAGAGAAGCAGATCCTGTGCGTGGGGCTAGTGGTGCTGGACGTCATCAGCCTGGTG
GACAAGTACCCTAAGGAGGACTCGGAGATAAGGTGTTTGTCCCAGAGATGGCAGCGCGGA
GGCAACGCGTCCAACTCCTGCACCGTTCTCTCCCTGCTCGGAGCCCCCTGTGCCTTCATG
GGCTCAATGGCTCCTGGCCATGTTGCTGATTTTGTCCTGGATGACCTCCGCCGCTATTCT
GTGGACCTACGCTACACAGTCTTTCAGACCACAGGCTCCGTCCCCATCGCCACGGTCATC
ATCAACGAGGCCAGTGGTAGCCGCACCATCCTATACTATGACAGGAGCCTGCCAGATGTG
TCTGCTACAGACTTTGAGAAGGTTGATCTGACCCAGTTCAAGTGGATCCACATTGAGGGC
CGGAACGCATCGGAGCAGGTGAAGATGCTGCAGCGGATAGACGCACACAACACCAGGCAG
CCTCCAGAGCAGAAGATCCGGGTGTCCGTGGAGGTGGAGAAGCCACGAGAGGAGCTCTTC
CAGCTGTTTGGCTACGGAGACGTGGTGTTTGTCAGCAAAGATGTGGCCAAGCACTTGGGG
TTCCAGTCAGCAGAGGAAGCCTTGAGGGGCTTGTATGGTCGTGTGAGGAAAGGGGCTGTG
CTTGTCTGTGCCTGGGCTGAGGAGGGCGCCGACGCCCTGGGCCCTGATGGCAAATTGCTC
CACTCGGATGCTTTCCCGCCACCCCGCGTGGTGGATACACTGGGAGCTGGAGACACCTTC
AATGCCTCCGTCATCTTCAGCCTCTCCCAGGGGAGGAGCGTGCAGGAAGCACTGAGATTC
GGGTGCCAGGTGGCCGGCAAGAAGTGTGGCCTGCAGGGCTTTGATGGCATCGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 298 |
| Molecular Weight
| 32730.055 |
| Theoretical pI
| 5.93 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ketohexokinase
MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM
GSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDV
SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF
QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL
HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
|
| External Links |
|---|
| GenBank ID Protein
| 4557693 |
| UniProtKB/Swiss-Prot ID
| P50053 |
| UniProtKB/Swiss-Prot Entry Name
| KHK_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_000221.2 |
| GeneCard ID
| KHK |
| GenAtlas ID
| KHK |
| HGNC ID
| HGNC:6315 |
| References |
|---|
| General References
| Not Available |