Identification
HMDB Protein ID CDBP01086
Secondary Accession Numbers Not Available
Name Myosin-IIIa
Description Not Available
Synonyms Not Available
Gene Name MYO3A
Protein Type Enzyme
Biological Properties
General Function Involved in motor activity
Specific Function Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing
GO Classification
Component
myosin complex
macromolecular complex
protein complex
Function
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
nucleoside-triphosphatase activity
protein serine/threonine kinase activity
hydrolase activity, acting on acid anhydrides
binding
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
catalytic activity
pyrophosphatase activity
hydrolase activity
transferase activity
motor activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
Cellular Location
  1. Cytoplasm
  2. cytoskeleton
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10p11.1
SNPs MYO3A
Gene Sequence
>4848 bp
ATGTTTCCATTAATTGGAAAAACAATCATCTTTGATAACTTTCCTGATCCTTCTGATACA
TGGGAAATCACTGAGACAATTGGCAAAGGAACTTATGGGAAAGTTTTTAAAGTATTGAAT
AAGAAAAATGGCCAAAAAGCAGCAGTCAAAATTCTTGATCCAATTCACGATATTGACGAA
GAGATTGAAGCAGAATATAACATCTTAAAAGCACTTTCTGACCACCCTAATGTGGTCAGA
TTCTATGGGATATACTTTAAGAAGGATAAAGTAAATGGAGACAAGCTGTGGTTGGTTCTT
GAGCTCTGCAGTGGAGGATCAGTGACTGACCTTGTGAAAGGATTTCTGAAGAGGGGTGAA
AGAATGAGTGAGCCTCTAATTGCCTATATTTTACATGAAGCACTAATGGGACTTCAACAT
TTGCATAACAACAAAACTATCCACAGAGATGTGAAAGGCAATAACATTCTATTGACCACG
GAAGGTGGAGTGAAACTAGTAGATTTTGGTGTGTCTGCACAGCTCACCAGTACCCGGCAC
CGTCGGAACACATCCGTAGGAACACCGTTTTGGATGGCTCCTGAGGTGATTGCATGTGAA
CAGCAATTGGATACCACTTATGACGCCAGATGTGACACTTGGTCCCTGGGTATCACGGCC
ATTGAGCTGGGTGATGGAGATCCTCCACTAGCTGACCTTCATCCCATGAGAGCACTCTTC
AAAATACCAAGGAATCCACCCCCAAAACTAAGGCAGCCTGAGCTATGGTCAGCAGAATTC
AATGACTTCATAAGCAAGTGCTTGACTAAAGATTATGAAAAGCGTCCAACAGTGTCAGAA
CTTTTACAGCATAAATTCATTACTCAAATTGAGGGCAAAGATGTGATGCTACAAAAACAA
CTAACGGAATTCATTGGCATCCATCAATGCATGGGAGGCACAGAAAAGGCCAGACGTGAA
CGTATTCACACGAAGAAAGGGAACTTCAACCGACCTCTAATATCCAATCTGAAGGATGTA
GATGATTTAGCAACCCTAGAAATTTTGGATGAGAATACAGTCTCAGAGCAACTTGAGAAG
TGTTATTCCAGAGATCAGATCTACGTCTATGTGGGAGACATACTCATTGCTCTTAACCCT
TTTCAGAGTCTGGGTCTTTACTCCACAAAGCATTCCAAACTATATATTGGATCAAAGAGA
ACTGCCAGTCCTCCTCACATTTTTGCAATGGCTGACTTAGGATATCAATCTATAATAACA
TATAATTCAGATCAGTGCATTGTTATTTCTGGAGAAAGTGGTGCTGGAAAGACTGAAAAT
GCTCATCTTTTAGTTCAGCAGCTGACAGTGCTTGGAAAGGCTAATAACAGAACCTTGCAA
GAGAAGATTTTACAAGTGAACAATTTGGTAGAAGCCTTTGGCAATGCCTGCACTATTATA
AATGACAATTCTAGCAGATTTGGAAAATACTTAGAAATGAAATTCACCTCTTCTGGAGCG
GTAGTGGGAGCACAGATTTCTGAATATCTCCTGGAAAAATCCCGAGTTATCCACCAAGCT
ATTGGAGAAAAAAATTTTCATATTTTTTACTACATTTATGCTGGTTTGGCTGAAAAGAAG
AAACTAGCCCATTACAAACTGCCTGAAAATAAGCCTCCCAGGTACCTACAAAATGACCAC
CTCAGAACAGTACAAGACATCATGAATAATAGTTTCTATAAATCCCAGTATGAATTAATT
GAGCAATGTTTCAAAGTCATAGGTTTTACAATGGAGCAACTTGGTAGTATATACAGCATA
CTCGCTGCAATCTTGAATGTTGGCAACATTGAATTTTCTTCTGTGGCAACTGAACACCAG
ATTGACAAGAGCCACATTTCTAATCATACAGCCCTGGAGAACTGTGTTTCTTTGCTTTGC
ATTCGGGCAGATGAGCTACAAGAAGCTCTCACCTCCCACTGTGTGGTCACTAGAGGAGAA
ACAATTATACGACCCAATACTGTAGAAAAAGCTACCGATGTCAGGGATGCCATGGCTAAA
ACTTTATATGGACGTCTCTTTAGTTGGATAGTCAATTGCATTAACAGTTTGTTGAAGCAT
GACTCATCACCAAGTGGGAATGGTGATGAGCTGAGCATTGGCATTCTTGATATATTTGGT
TTTGAAAATTTCAAAAAAAATTCCTTCGAGCAGCTGTGCATTAACATTGCAAATGAACAA
ATTCAGTATTATTATAATCAACATGTGTTTGCATGGGAACAGAATGAATACCTAAATGAA
GATGTGGATGCTAGAGTTATTGAATATGAGGATAACTGGCCCCTCTTAGATATGTTTCTG
CAAAAGCCAATGGGTTTACTTTCCCTACTTGATGAAGAAAGTAGATTTCCCAAGGCCACT
GACCAGACTCTTGTAGAAAAATTTGAAGGTAACCTGAAATCACAATACTTCTGGAGACCC
AAAAGAATGGAACTTAGTTTTGGAATTCACCATTATGCAGGAAAGGTCCTCTATAATGCA
AGTGGATTCTTAGCCAAAAACAAGACACTAGTTCCTACTGACATTGTGCTACTTTTGAGG
TCATCCGACAACAGTGTAATTAGGCAACTAGTCAACCACCCTCTGACCAAAACAGGTAAT
CTGCCACATTCTAAACTAAAAATGTTAAACTATCAAATGAGGACTTCAGAAAAATTAATC
AACCTGGCAAAGGGCGACACTGGAGAAGCCACACGTCATGCCAGAGAGACAACCAACATG
AAAACACAAACGGTTGCATCATATTTTAGATATTCCCTGATGGATTTGTTGTCTAAAATG
GTGGTGGGCCAACCTCATTTTGTCCGTTGCATCAAACCAAATAGTGAGCGTCAGGCAAGA
AAATATGACAAAGAGAAAGTTCTGCTACAGCTTCGGTACACAGGAATTCTGGAAACAGCA
AGAATTCGAAGACTAGGATTCTCCCATCGGATACTTTTTGCTAACTTTATAAAGCGGTAC
TACCTTCTCTGCTACAAGTCGAGCGAGGAGCCCCGCATGAGCCCTGACACCTGTGCCACC
ATTTTGGAAAAAGCTGGTCTCGATAACTGGGCTCTTGGAAAAACAAAAGTGTTCCTTAAG
TATTATCACGTGGAGCAGTTAAATCTAATGCGAAAGGAAGCTATTGACAAGCTTATTTTG
ATTCAAGCTTGTGTCAGAGCATTCTTGTGTTCAAGAAGATACCAAAAAATACAGGAGAAA
AGGAAAGAAAGCGCTATAATAATACAGTCAGCTGCAAGAGGACACCTTGTCGGGAAACAA
AGAAAAGAAATTGTTGACATGAAAAACACAGCAGTAACAACCATTCAAACTTCTGATCAG
GAATTCGACTACAAGAAAAACTTTGAAAATACAAGGGAATCTTTCGTGAAGAAACAAGCA
GAAAATGCAATCTCTGCTAATGAAAGATTCATTTCAGCTCCAAATAATAAAGGAAGTGTA
TCTGTAGTGAAGACTTCCACTTTCAAACCTGAAGAGGAAACCACCAATGCTGTGGAGAGT
AACAACAGAGTGTATCAGACTCCAAAAAAAATGAATAATGTGTATGAGGAAGAGGTTAAG
CAAGAATTTTACCTTGTAGGGCCAGAAGTAAGCCCCAAACAGAAGTTTGTCAAAGACCTG
GAAGAGAACAGCAATCTAAGGAAAGTGGAGAAAGAGGAAGCTATGATCCAGAGTTACTAT
CAGAGGTACACAGAGGAGAGGAATTGTGAAGAGTCAAAAGCAGCATATCTAGAAAGGAAG
GCCATATCAGAAAGGCCAAGCTACCCAGTGCCTTGGTTAGCTGAAAATGAGACTTCCTTT
AAAAAAACTTTGGAACCTACACTTAGCCAAAGGTCAATTTATCAAAATGCAAACAGCATG
GAAAAAGAAAAGAAGACATCTGTAGTTACCCAGAGTGCACCGATATGCAGCCAGGAGGAA
GGCAGAGGCCGTCTGAGGCATGAGACAGTCAAAGAGAGGCAAGTTGAACCAGTGACACAG
GCCCAGGAGGAAGAAGATAAAGCAGCGGTATTCATTCAGAGCAAATACCGGGGTTACAAG
AGAAGGCAGCAGTTGAGGAAGGACAAGATGTCTTCTTTTAAGCATCAGAAGATTGTCACA
ACACCAACAGAAGTAGCAAGAAACACTCATAATTTGTATTCCTATCCCACAAAACATGAG
GAAATCAATAACATCAAGAAGAAGGATAACAAAGACTCGAAAGCAACTTCAGAAAGAGAA
GCATGTGGTTTGGCAATTTTTTCAAAACAGATATCAAAGTTATCTGAAGAATATTTCATT
CTGCAGAAAAAATTGAATGAAATGATTTTGTCACAGCAACTGAAGTCACTTTATCTGGGT
GTCTCGCACCATAAGCCAATTAATAGACGAGTTTCTTCTCAGCAGTGCCTCTCAGGTGTC
TGTAAAGGAGAGGAGCCAAAAATATTGAGACCCCCAAGACGACCCCGGAAACCCAAAACA
TTAAATAACCCTGAAGACTCCACATACTATTATCTACTTCATAAGTCAATCCAAGAAGAA
AAACGAAGACCAAGGAAAGACAGTCAGGGAAAATTATTAGATTTGGAAGATTTCTATTAT
AAGGAATTTTTGCCCAGTCGTTCTGGACCAAAGGAACATAGCCCTAGTTTAAGAGAACGA
AGACCACAGCAAGAACTCCAGAATCAATGTATTAAGGCTAATGAAAGGTGCTGGGCGGCG
GAGAGCCCCGAGAAGGAGGAGGAGAGAGAGCCAGCAGCCAACCCCTACGACTTCAGGAGG
CTCCTGCGCAAAACCTCCCAGCGCCGGCGCCTCGTCCAGCAGTCCTAA
Protein Properties
Number of Residues 1616
Molecular Weight 186207.0
Theoretical pI 9.25
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Myosin-IIIa
MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDE
EIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGE
RMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRH
RRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALF
KIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQ
LTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEK
CYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMIT
YNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTII
NDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKK
KLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSI
LAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGE
TIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFG
FENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFL
QKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNA
SGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKL
INLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQA
RKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCA
TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE
KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ
AENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEV
KQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLER
KAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE
EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV
TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYF
ILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPK
TLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRE
RRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS
GenBank ID Protein 7958618
UniProtKB/Swiss-Prot ID Q8NEV4
UniProtKB/Swiss-Prot Entry Name MYO3A_HUMAN
PDB IDs Not Available
GenBank Gene ID AF229172
GeneCard ID MYO3A
GenAtlas ID MYO3A
HGNC ID HGNC:7601
References
General References Not Available