Cannabis Compound Database: Showing Protein N-acetylgalactosamine kinase (CDBP01071)

Identification Biological properties Gene properties Protein properties External links References XML Show 5 compounds

Identification

HMDB Protein ID

CDBP01071

Secondary Accession Numbers

Not Available

Name

N-acetylgalactosamine kinase

Description

Not Available

Synonyms

GalNAc kinase
Galactokinase 2

Gene Name

GALK2

Protein Type

Enzyme

Biological Properties

General Function

Involved in galactokinase activity

Specific Function

Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.

GO Classification

Biological Process
galactose metabolic process
Cellular Component
cytoplasm
Component
cell part
intracellular part
cytoplasm
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
phosphotransferase activity, alcohol group as acceptor
galactokinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
Molecular Function
ATP binding
galactokinase activity
N-acetylgalactosamine kinase activity
Process
hexose metabolic process
phosphorylation
carbohydrate phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
galactose metabolic process
cellular metabolic process
small molecule metabolic process
alcohol metabolic process
monosaccharide metabolic process

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Amino sugar and nucleotide sugar metabolism	Not Available

Gene Properties

Chromosome Location

Locus

15q21.1-q21.2

SNPs

GALK2

Gene Sequence

>1377 bp
ATGGCTACAGAGAGCCCTGCTACGCGTCGGGTCCAGGTGGCAGAACATCCTAGGTTACTG
AAGCTAAAGGAGATGTTTAACTCCAAGTTTGGATCTATTCCCAAGTTTTATGTTCGAGCA
CCAGGAAGAGTCAACATAATAGGAGAGCATATAGATTATTGTGGATATTCTGTTCTTCCT
ATGGCTGTAGAACAAGATGTGCTAATAGCTGTAGAACCTGTGAAAACGTACGCTCTCCAA
CTGGCCAATACAAATCCCTTGTATCCGGACTTCAGTACTAGTGCTAATAACATCCAGATT
GATAAAACCAAGCCTTTGTGGCACAACTATTTCTTATGTGGACTTAAAGGAATTCAGGAA
CACTTTGGTCTTAGTAACCTGACTGGAATGAACTGCCTGGTAGATGGAAATATCCCACCA
AGTTCTGGCCTCTCCAGCTCCAGTGCTTTGGTCTGTTGTGCTGGCTTGGTGACGCTCACA
GTGCTGGGAAGGAATCTATCCAAGGTGGAACTTGCAGAAATCTGTGCCAAGAGTGAGCGT
TACATTGGCACTGAAGGAGGAGGCATGGACCAGTCTATATCATTTCTTGCAGAAGAAGGA
ACTGCCAAGTTGATAGAATTTAGTCCTCTGAGGGCAACCGATGTAAAACTCCCAAGTGGA
GCAGTGTTTGTGATTGCCAACAGTTGTGTGGAGATGAATAAGGCAGCAACTTCCCATTTC
AATATCAGGGTGATGGAGTGTCGGCTGGCTGCGAAGCTCCTGGCTAAATACAAAAGCTTG
CAATGGGACAAAGTACTGAGGCTGGAGGAGGTGCAGGCTAAACTAGGGATTAGTCTAGAA
GAAATGCTGTTGGTCACAGAAGATGCCCTTCATCCTGAACCCTATAACCCTGAGGAGATC
TGCAGGTGTCTGGGAATTAGCCTGGAGGAACTCCGAACCCAAATCCTGAGTCCAAACACT
CAAGATGTGCTCATCTTCAAACTCTATCAGCGGGCAAAGCATGTGTACAGCGAGGCTGCG
CGAGTGCTCCAGTTTAAGAAGATATGTGAAGAAGCACCTGAAAACATGGTCCAGCTGCTG
GGAGAGTTGATGAACCAGAGCCACATGAGCTGCCGGGACATGTATGAGTGCAGCTGCCCC
GAGCTGGATCAGCTGGTGGACATCTGTCGGAAGTTTGGGGCTCAAGGGTCACGACTTACT
GGAGCAGGATGGGGAGGCTGTACAGTATCAATGGTACCTGCGGACAAGCTGCCCAGCTTT
CTAGCAAATGTGCACAAAGCTTATTACCAGAGGAGTGATGGAAGCTTAGCACCGGAGAAG
CAAAGTTTGTTTGCTACCAAACCTGGAGGTGGGGCTTTGGTTTTGCTTGAGGCCTGA

Protein Properties

Number of Residues

458

Molecular Weight

49234.57

Theoretical pI

6.364

Pfam Domain Function

GHMP_kinases_C (PF08544 )
GHMP_kinases_N (PF00288 )
GalKase_gal_bdg (PF10509 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>N-acetylgalactosamine kinase
MATESPATRRVQVAEHPRLLKLKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLP
MAVEQDVLIAVEPVKTYALQLANTNPLYPDFSTSANNIQIDKTKPLWHNYFLCGLKGIQE
HFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSER
YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAATSHF
NIRVMECRLAAKLLAKYKSLQWDKVLRLEEVQAKLGISLEEMLLVTEDALHPEPYNPEEI
CRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHVYSEAARVLQFKKICEEAPENMVQLL
GELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSF
LANVHKAYYQRSDGSLAPEKQSLFATKPGGGALVLLEA

External Links

GenBank ID Protein

13477333

UniProtKB/Swiss-Prot ID

Q01415

UniProtKB/Swiss-Prot Entry Name

GALK2_HUMAN

PDB IDs