Showing Protein UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (CDBP01030)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01030
Secondary Accession Numbers Not Available
Name UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Description Not Available
Synonyms
  1. G1PT
  2. GPT
  3. GlcNAc-1-P transferase
  4. N-acetylglucosamine-1-phosphate transferase
Gene Name DPAGT1
Protein Type Enzyme
Biological Properties
General Function Involved in phospho-N-acetylmuramoyl-pentapeptide-transferase activity
Specific Function Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
GO Classification
Biological Process
post-translational protein modification
protein N-linked glycosylation via asparagine
protein oligomerization
UDP-N-acetylglucosamine metabolic process
dolichol biosynthetic process
dolichol-linked oligosaccharide biosynthetic process
Cellular Component
integral to endoplasmic reticulum membrane
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, for other substituted phosphate groups
phospho-n-acetylmuramoyl-pentapeptide-transferase activity
Molecular Function
transferase activity, transferring glycosyl groups
phospho-N-acetylmuramoyl-pentapeptide-transferase activity
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 11
Locus 11q23.3
SNPs DPAGT1
Gene Sequence 
>1227 bp
ATGTGGGCCTTCTCGGAATTGCCCATGCCGCTGCTGATCAATTTGATCGTCTCGCTGCTG
GGATTTGTGGCCACAGTCACCCTCATCCCGGCCTTCCGGGGCCACTTCATTGCTGCGCGC
CTCTGTGGTCAGGACCTCAACAAAACCAGCCGACAGCAGATCCCAGAATCCCAGGGAGTG
ATCAGCGGTGCTGTTTTCCTTATCATCCTCTTCTGCTTCATCCCTTTCCCCTTCCTGAAC
TGCTTTGTGAAGGAGCAGTGTAAGGCATTCCCCCACCATGAATTTGTGGCCCTGATAGGT
GCCCTCCTTGCCATCTGCTGCATGATCTTCCTGGGCTTTGCGGATGATGTACTGAATCTG
CGCTGGCGCCATAAGCTGCTGCTACATACAGCTGCCTCACTACCTCTCCTCATGGTATAT
TTCACCAACTTTGGCAACACGACCATTGTGGTGCCCAAGCCTTTCCGCCCGATACTTGGC
CTGCATCTGGACTTGGGAATCCTGTACTATGTCTACATGGGGCTGCTGGCAGTGTTCTGT
ACCAATGCCATCAATATCCTAGCAGGAATTAACGGCCTAGAGGCTGGCCAGTCACTAGTC
ATTTCTGCTTCCATCATTGTCTTCAACCTGGTAGAGTTGGAAGGTGATTGTCGGGATGAT
CATGTCTTTTCCCTCTACTTCATGATACCCTTTTTTTTCACCACTTTGGGATTGCTCTAC
CACAACTGGTACCCATCACGGGTGTTTGTGGGAGATACCTTCTGTTACTTTGCTGGCATG
ACCTTTGCCGTGGTGGGCATCTTGGGACACTTCAGCAAGACCATGCTACTATTCTTCATG
CCCCAGGTGTTCAACTTCCTCTACTCACTGCCTCAGCTCCTGCATATCATCCCCTGCCCT
CGCCACCGCATACCCAGACTCAATATCAAGACAGGCAAACTGGAGATGAGCTATTCCAAG
TTCAAGACCAAGAGCCTCTCTTTCTTGGGCACCTTTATTTTAAAGGTGGCAGAGAGCCTC
CAGCTGGTGACAGTACACCAGAGTGAGACTGAAGATGGTGAATTCACTGAATGTAACAAC
ATGACCCTCATCAACTTGCTACTTAAAGTCCTTGGGCCCATACATGAGAGAAACCTCACA
TTGCTCCTGCTGCTGCTGCAGATCCTGGGCAGTGCCATCACCTTCTCCATTCGATATCAG
CTCGTTCGACTCTTCTATGATGTCTGA
Protein Properties
Number of Residues 408
Molecular Weight 46089.485
Theoretical pI 7.997
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV
ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC
TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY
HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN
MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV
GenBank ID Protein 12002052
UniProtKB/Swiss-Prot ID Q9H3H5
UniProtKB/Swiss-Prot Entry Name GPT_HUMAN
PDB IDs Not Available
GenBank Gene ID AF070443
GeneCard ID DPAGT1
GenAtlas ID DPAGT1
HGNC ID HGNC:2995
References
General References Not Available