| Identification |
|---|
| HMDB Protein ID
| CDBP01006 |
| Secondary Accession Numbers
| Not Available |
| Name
| Inorganic pyrophosphatase |
| Description
| Not Available |
| Synonyms
|
- PPase
- Pyrophosphate phospho-hydrolase
|
| Gene Name
| PPA1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in magnesium ion binding |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| phosphate-containing compound metabolic process |
| diphosphate metabolic process |
| tRNA aminoacylation for protein translation |
| Cellular Component |
| cytosol |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| hydrolase activity |
| magnesium ion binding |
| inorganic diphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| Molecular Function |
| magnesium ion binding |
| inorganic diphosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Oxidative phosphorylation | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10q11.1-q24 |
| SNPs
| PPA1 |
| Gene Sequence
|
>870 bp
ATGAGCGGCTTCAGCACCGAGGAGCGCGCCGCGCCCTTCTCCCTGGAGTACCGAGTCTTC
CTCAAAAATGAGAAAGGACAATATATATCTCCATTTCATGATATTCCAATTTATGCAGAT
AAGGATGTGTTTCACATGGTAGTTGAAGTACCACGCTGGTCTAATGCAAAAATGGAGATT
GCTACAAAGGACCCTTTAAACCCTATTAAACAAGATGTGAAAAAAGGAAAACTTCGCTAT
GTTGCGAATTTGTTCCCGTATAAAGGATATATCTGGAACTATGGTGCCATCCCTCAGACT
TGGGAAGACCCAGGGCACAATGATAAACATACTGGCTGTTGTGGTGACAATGACCCAATT
GATGTGTGTGAAATTGGAAGCAAGGTATGTGCAAGAGGTGAAATAATTGGCGTGAAAGTT
CTAGGCATATTGGCTATGATTGACGAAGGGGAAACCGACTGGAAAGTCATTGCCATTAAT
GTGGATGATCCTGATGCAGCCAATTATAATGATATCAATGATGTCAAACGGCTGAAACCT
GGCTACTTAGAAGCTACTGTGGACTGGTTTAGAAGGTATAAGGTTCCTGATGGAAAACCA
GAAAATGAGTTTGCGTTTAATGCAGAATTTAAAGATAAGGACTTTGCCATTGATATTATT
AAAAGCACTCATGACCATTGGAAAGCATTAGTGACTAAGAAAACGAATGGAAAAGGAATC
AGTTGCATGAATACAACTTTGTCTGAGAGCCCCTTCAAGTGTGATCCTGATGCTGCCAGA
GCCATTGTGGATGCTTTACCACCACCCTGTGAATCTGCCTGCACAGTACCAACAGACGTG
GATAAGTGGTTCCATCACCAGAAAAACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 289 |
| Molecular Weight
| 32659.77 |
| Theoretical pI
| 5.858 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Inorganic pyrophosphatase
MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI
ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI
DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP
GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI
SCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q15181 |
| UniProtKB/Swiss-Prot Entry Name
| IPYR_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF154065 |
| GeneCard ID
| PPA1 |
| GenAtlas ID
| PPA1 |
| HGNC ID
| HGNC:9226 |
| References |
|---|
| General References
| Not Available |