974 CDBP00973 Cytochrome P450 2C9 P11712 CP2C9_HUMAN false false Metal Binding Homo_sapiens CYP2C9 490 55627.365 7.907 Involved in monooxygenase activity Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan. 1OG2;1OG5;1R9O AY341248 32891803 CYP2C9 10 10q24 CYP2C9 HGNC:2623 true hsa:1559 NP_000762.2:NM_000771.3 Heme group 2020-06-12T23:06:53Z 2020-07-28T02:31:56Z 0 1 0