Identification |
HMDB Protein ID
| CDBP00950 |
Secondary Accession Numbers
| Not Available |
Name
| Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial |
Description
| Not Available |
Synonyms
|
- Cob(I)alamin adenosyltransferase
- Methylmalonic aciduria type B protein
|
Gene Name
| MMAB |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ATP binding |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
cobalamin biosynthetic process |
Cellular Component |
mitochondrion |
Function |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
cob(i)yrinic acid a,c-diamide adenosyltransferase activity |
transferase activity, transferring alkyl or aryl (other than methyl) groups |
binding |
catalytic activity |
transferase activity |
Molecular Function |
ATP binding |
cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
Process |
metabolic process |
nitrogen compound metabolic process |
tetrapyrrole metabolic process |
porphyrin metabolic process |
cobalamin biosynthetic process |
porphyrin biosynthetic process |
|
Cellular Location
|
- Mitochondrion (Probable)
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | adenosylcobalamin biosynthesis | Not Available | Not Available | Porphyrin and chlorophyll metabolism | Not Available | |
|
Gene Properties |
Chromosome Location
| 12 |
Locus
| 12q24 |
SNPs
| MMAB |
Gene Sequence
|
>753 bp
ATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCAAGGG
TGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGGCGTG
GAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTACACC
AAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGATGAC
CAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGCTCTG
GAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTGCACA
TTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCACTTA
AAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAAGTAC
ACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAGCTCG
GCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCTTGTC
CAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTATCTC
TTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAGAGAAAATATACAAGAAA
AATGACCCATCGGCCGAGTCTGAGGGACTCTGA
|
Protein Properties |
Number of Residues
| 250 |
Molecular Weight
| 27387.975 |
Theoretical pI
| 8.606 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYT
KTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCT
LQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISS
ALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK
NDPSAESEGL
|
External Links |
GenBank ID Protein
| 127802458 |
UniProtKB/Swiss-Prot ID
| Q96EY8 |
UniProtKB/Swiss-Prot Entry Name
| MMAB_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| BC005054 |
GeneCard ID
| MMAB |
GenAtlas ID
| MMAB |
HGNC ID
| HGNC:19331 |
References |
General References
| Not Available |