Identification
HMDB Protein ID CDBP00950
Secondary Accession Numbers Not Available
Name Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
Description Not Available
Synonyms
  1. Cob(I)alamin adenosyltransferase
  2. Methylmalonic aciduria type B protein
Gene Name MMAB
Protein Type Enzyme
Biological Properties
General Function Involved in ATP binding
Specific Function Not Available
GO Classification
Biological Process
cobalamin biosynthetic process
Cellular Component
mitochondrion
Function
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
cob(i)yrinic acid a,c-diamide adenosyltransferase activity
transferase activity, transferring alkyl or aryl (other than methyl) groups
binding
catalytic activity
transferase activity
Molecular Function
ATP binding
cob(I)yrinic acid a,c-diamide adenosyltransferase activity
Process
metabolic process
nitrogen compound metabolic process
tetrapyrrole metabolic process
porphyrin metabolic process
cobalamin biosynthetic process
porphyrin biosynthetic process
Cellular Location
  1. Mitochondrion (Probable)
Pathways
Gene Properties
Chromosome Location 12
Locus 12q24
SNPs MMAB
Gene Sequence
>753 bp
ATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCAAGGG
TGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGGCGTG
GAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTACACC
AAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGATGAC
CAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGCTCTG
GAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTGCACA
TTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCACTTA
AAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAAGTAC
ACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAGCTCG
GCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCTTGTC
CAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTATCTC
TTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAGAGAAAATATACAAGAAA
AATGACCCATCGGCCGAGTCTGAGGGACTCTGA
Protein Properties
Number of Residues 250
Molecular Weight 27387.975
Theoretical pI 8.606
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYT
KTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCT
LQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISS
ALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK
NDPSAESEGL
GenBank ID Protein 127802458
UniProtKB/Swiss-Prot ID Q96EY8
UniProtKB/Swiss-Prot Entry Name MMAB_HUMAN
PDB IDs
GenBank Gene ID BC005054
GeneCard ID MMAB
GenAtlas ID MMAB
HGNC ID HGNC:19331
References
General References Not Available