| Identification |
|---|
| HMDB Protein ID
| CDBP00930 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome b-c1 complex subunit 6, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- Complex III subunit 6
- Complex III subunit VIII
- Cytochrome c1 non-heme 11 kDa protein
- Mitochondrial hinge protein
- Ubiquinol-cytochrome c reductase complex 11 kDa protein
|
| Gene Name
| UQCRH |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in ubiquinol-cytochrome-c reductase activity |
| Specific Function
| This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 |
| GO Classification
|
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| hydrogen ion transmembrane transporter activity |
| ubiquinol-cytochrome-c reductase activity |
| transporter activity |
| Process |
| generation of precursor metabolites and energy |
| electron transport chain |
| respiratory electron transport chain |
| cellular metabolic process |
| mitochondrial electron transport, ubiquinol to cytochrome c |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion inner membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p34.1 |
| SNPs
| UQCRH |
| Gene Sequence
|
>276 bp
ATGGGACTGGAGGACGAGCAAAAGATGCTTACCGAATCCGGAGATCCTGAGGAGGAGGAA
GAGGAAGAGGAGGAATTAGTGGATCCCCTAACAACAGTGAGAGAGCAATGCGAGCAGTTG
GAGAAATGTGTAAAGGCCCGGGAGCGGCTAGAGCTCTGTGATGAGCGTGTATCCTCTCGA
TCACATACAGAAGAGGATTGCACGGAGGAGCTCTTTGACTTCTTGCATGCGAGGGACCAT
TGCGTGGCCCACAAACTCTTTAACAACTTGAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 91 |
| Molecular Weight
| 10738.7 |
| Theoretical pI
| 4.1 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cytochrome b-c1 complex subunit 6, mitochondrial
MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELCDERVSSR
SHTEEDCTEELFDFLHARDHCVAHKLFNNLK
|
| External Links |
|---|
| GenBank ID Protein
| 189065183 |
| UniProtKB/Swiss-Prot ID
| P07919 |
| UniProtKB/Swiss-Prot Entry Name
| QCR6_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK311967 |
| GeneCard ID
| UQCRH |
| GenAtlas ID
| UQCRH |
| HGNC ID
| HGNC:12590 |
| References |
|---|
| General References
| Not Available |