Cannabis Compound Database: Showing Protein Fructose-bisphosphate aldolase A (CDBP00916)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP00916

Secondary Accession Numbers

Not Available

Name

Fructose-bisphosphate aldolase A

Description

Not Available

Synonyms

Lung cancer antigen NY-LU-1
Muscle-type aldolase

Gene Name

ALDOA

Protein Type

Enzyme

Biological Properties

General Function

Involved in fructose-bisphosphate aldolase activity

Specific Function

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).

GO Classification

Biological Process
regulation of cell shape
striated muscle contraction
glycolysis
gluconeogenesis
protein homotetramerization
actin filament organization
ATP biosynthetic process
fructose 1,6-bisphosphate metabolic process
fructose metabolic process
muscle cell homeostasis
platelet activation
platelet degranulation
Cellular Component
cytosol
actin cytoskeleton
I band
platelet alpha granule lumen
extracellular vesicular exosome
Function
catalytic activity
lyase activity
carbon-carbon lyase activity
aldehyde-lyase activity
fructose-bisphosphate aldolase activity
Molecular Function
fructose binding
fructose-bisphosphate aldolase activity
tubulin binding
identical protein binding
actin binding
Process
metabolic process
small molecule metabolic process
alcohol metabolic process
monosaccharide metabolic process
hexose metabolic process
glucose metabolic process
glucose catabolic process
glycolysis

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycolysis / Gluconeogenesis	Not Available
Fructose and mannose metabolism	Not Available
HIF-1 signaling pathway	Not Available
Fructose and Mannose Degradation
Fructosuria		Not Available

Gene Properties

Chromosome Location

Locus

16p11.2

SNPs

ALDOA

Gene Sequence

>1095 bp
ATGCCCTACCAATATCCAGCACTGACCCCGGAGCAGAAGAAGGAGCTGTCTGACATCGCT
CACCGCATCGTGGCACCTGGCAAGGGCATCCTGGCTGCAGATGAGTCCACTGGGAGCATT
GCCAAGCGGCTGCAGTCCATTGGCACCGAGAACACCGAGGAGAACCGGCGCTTCTACCGC
CAGCTGCTGCTGACAGCTGACGACCGCGTGAACCCCTGCATTGGGGGTGTCATCCTCTTC
CATGAGACACTCTACCAGAAGGCGGATGATGGGCGTCCCTTCCCCCAAGTTATCAAATCC
AAGGGCGGTGTTGTGGGCATCAAGGTAGACAAGGGCGTGGTCCCCCTGGCAGGGACAAAT
GGCGAGACTACCACCCAAGGGTTGGATGGGCTGTCTGAGCGCTGTGCCCAGTACAAGAAG
GACGGAGCTGACTTCGCCAAGTGGCGTTGTGTGCTGAAGATTGGGGAACACACCCCCTCA
GCCCTCGCCATCATGGAAAATGCCAATGTTCTGGCCCGTTATGCCAGTATCTGCCAGCAG
AATGGCATTGTGCCCATCGTGGAGCCTGAGATCCTCCCTGATGGGGACCATGACTTGAAG
CGCTGCCAGTATGTGACCGAGAAGGTGCTGGCTGCTGTCTACAAGGCTCTGAGTGACCAC
CACATCTACCTGGAAGGCACCTTGCTGAAGCCCAACATGGTCACCCCAGGCCATGCTTGC
ACTCAGAAGTTTTCTCATGAGGAGATTGCCATGGCGACCGTCACAGCGCTGCGCCGCACA
GTGCCCCCCGCTGTCACTGGGATCACCTTCCTGTCTGGAGGCCAGAGTGAGGAGGAGGCG
TCCATCAACCTCAATGCCATTAACAAGTGCCCCCTGCTGAAGCCCTGGGCCCTGACCTTC
TCCTACGGCCGAGCCCTGCAGGCCTCTGCCCTGAAGGCCTGGGGCGGGAAGAAGGAGAAC
CTGAAGGCTGCGCAGGAGGAGTATGTCAAGCGAGCCCTGGCCAACAGCCTTGCCTGTCAA
GGAAAGTACACTCCGAGCGGTCAGGCTGGGGCTGCTGCCAGCGAGTCCCTCTTCGTCTCT
AACCACGCCTATTAA

Protein Properties

Number of Residues

364

Molecular Weight

39419.675

Theoretical pI

8.084

Pfam Domain Function

Glycolytic (PF00274 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Fructose-bisphosphate aldolase A
MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYR
QLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTN
GETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQ
NGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHAC
TQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTF
SYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVS
NHAY

External Links

GenBank ID Protein

178351

UniProtKB/Swiss-Prot ID

P04075

UniProtKB/Swiss-Prot Entry Name

ALDOA_HUMAN

PDB IDs

GenBank Gene ID

M11560

GeneCard ID

ALDOA