| Identification |
|---|
| HMDB Protein ID
| CDBP00888 |
| Secondary Accession Numbers
| Not Available |
| Name
| Putative deoxyribose-phosphate aldolase |
| Description
| Not Available |
| Synonyms
|
- DERA
- Deoxyriboaldolase
- Phosphodeoxyriboaldolase
- 2-deoxy-D-ribose 5-phosphate aldolase
|
| Gene Name
| DERA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (By similarity).
|
| GO Classification
|
| Biological Process |
| deoxyribonucleotide catabolic process |
| deoxyribose phosphate catabolic process |
| deoxyribonucleoside catabolic process |
| Cellular Component |
| cytoplasm |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| catalytic activity |
| lyase activity |
| carbon-carbon lyase activity |
| aldehyde-lyase activity |
| deoxyribose-phosphate aldolase activity |
| Molecular Function |
| deoxyribose-phosphate aldolase activity |
| Process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| nucleotide catabolic process |
| deoxyribonucleotide catabolic process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Pentose Phosphate Pathway |    |  | | 2-deoxy-D-ribose 1-phosphate degradation | Not Available | Not Available | | Glucose-6-phosphate dehydrogenase deficiency |    | Not Available | | Ribose-5-phosphate isomerase deficiency |    | Not Available | | Transaldolase deficiency |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 12 |
| Locus
| 12p12.3 |
| SNPs
| DERA |
| Gene Sequence
|
>957 bp
ATGTCCGCGCACAATCGGGGCACCGAGCTCGACCTTAGCTGGATCTCCAAAATACAAGTG
AATCACCCGGCAGTTCTGAGGCGTGCGGAACAAATCCAGGCTCGCAGAACCGTGAAAAAG
GAGTGGCAGGCTGCTTGGCTCCTGAAAGCTGTTACCTTTATAGATCTTACTACACTTTCA
GGTGATGATACATCTTCCAACATTCAAAGGCTCTGTTATAAAGCCAAATACCCAATCCGG
GAAGATCTCTTAAAAGCTTTAAATATGCATGATAAAGGCATTACTACAGCCGCCGTTTGT
GTTTATCCCGCCCGGGTGTGTGATGCTGTAAAAGCACTCAAGGCTGCAGGCTGTAATATC
CCTGTGGCATCAGTGGCCGCTGGATTTCCAGCTGGACAGACTCATTTGAAGACACGATTA
GAAGAGATCAGATTGGCTGTGGAAGATGGAGCTACAGAAATCGACGTGGTAATTAACAGA
AGCTTGGTGCTGACAGGCCAGTGGGAAGCCCTGTATGATGAGATTCGTCAGTTTCGCAAG
GCCTGTGGGGAGGCTCATCTTAAAACTATATTAGCGACAGGAGAACTTGGAACTCTTACT
AATGTCTATAAAGCCAGTATGATAGCAATGATGGCAGGATCAGATTTTATTAAGACCTCT
ACTGGAAAAGAAACAGTAAATGCCACCTTCCCGGTAGCTATAGTAATGCTGCGGGCCATT
AGAGATTTCTTCTGGAAAACTGGAAACAAGATAGGGTTTAAACCAGCAGGAGGCATCCGC
AGTGCAAAGGATTCCCTTGCTTGGCTCTCTCTTGTAAAGGAGGAGCTTGGAGATGAGTGG
CTGAAGCCAGAACTCTTTCGAATAGGTGCCAGTACTCTGCTCTCGGACATTGAGAGGCAG
ATTTACCATCATGTGACTGGAAGATATGCAGCTTATCATGATCTTCCAATGTCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 318 |
| Molecular Weight
| 35230.395 |
| Theoretical pI
| 8.946 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Putative deoxyribose-phosphate aldolase
MSAHNRGTELDLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLS
GDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNI
PVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRK
ACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAI
RDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEWLKPELFRIGASTLLSDIERQ
IYHHVTGRYAAYHDLPMS
|
| External Links |
|---|
| GenBank ID Protein
| 116063554 |
| UniProtKB/Swiss-Prot ID
| Q9Y315 |
| UniProtKB/Swiss-Prot Entry Name
| DEOC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015954.2 |
| GeneCard ID
| DERA |
| GenAtlas ID
| DERA |
| HGNC ID
| HGNC:24269 |
| References |
|---|
| General References
| Not Available |