<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">875</id>
  <cancdbp-id>CDBP00874</cancdbp-id>
  <name>Geranylgeranyl pyrophosphate synthase</name>
  <uniprot-id>O95749</uniprot-id>
  <uniprot-name>GGPPS_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>GGPS1</gene-name>
  <num-residues type="integer">300</num-residues>
  <molecular-weight type="decimal">34870.625</molecular-weight>
  <theoretical-pi type="decimal">6.14</theoretical-pi>
  <general-function>Involved in isoprenoid biosynthetic process</general-function>
  <specific-function>Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids>2Q80</pdb-ids>
  <genbank-gene-id>AB017971</genbank-gene-id>
  <genbank-protein-id nil="true"/>
  <genecard-id>GGPS1</genecard-id>
  <chromosome-location>1</chromosome-location>
  <locus>1q43</locus>
  <geneatlas-id>GGPS1</geneatlas-id>
  <hgnc-id>HGNC:4249</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:9453</kegg-id>
  <meta-cyc-id>HS07859-MONOMER</meta-cyc-id>
  <ncbi-sequence-ids>NP_001032354.1:NM_001037277.1</ncbi-sequence-ids>
  <tissue-specificity>Abundantly expressed in testis. Found in other tissues to a lower extent.
</tissue-specificity>
  <cofactor>magnesium ions</cofactor>
  <subunit>Homohexamer; trimer of homodimers
</subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:52Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:26:07Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">1</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

