870 CDBP00869 Nitric oxide synthase, inducible P35228 NOS2_HUMAN true true Enzyme Homo_sapiens NOS2 1153 131116.3 7.954 Involved in oxidoreductase activity Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2. 1NSI;2LL6;2NSI;3E7G;3EJ8;3HR4;4NOS L24553 24041029 NOS2 17 17q11.2-q12 NOS2 HGNC:7873 true hsa:4843 HS00205-MONOMER NP_000616.3:NM_000625.4 Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets. Heme group;FAD;FMN;Tetrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme Homodimer. Binds SLC9A3R1 2020-06-12T23:06:52Z 2020-07-28T02:26:06Z 0 1 0