Cannabis Compound Database: Showing Protein Phosphoserine phosphatase (CDBP00830)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP00830

Secondary Accession Numbers

Not Available

Name

Phosphoserine phosphatase

Description

Not Available

Synonyms

L-3-phosphoserine phosphatase
O-phosphoserine phosphohydrolase
PSP
PSPase

Gene Name

PSPH

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.

GO Classification

Biological Process
response to mechanical stimulus
response to testosterone stimulus
response to nutrient levels
L-serine biosynthetic process
cellular nitrogen compound metabolic process
Cellular Component
cytosol
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoserine phosphatase activity
phosphoric ester hydrolase activity
phosphatase activity
Molecular Function
magnesium ion binding
phosphoserine phosphatase activity
calcium ion binding
Process
serine family amino acid metabolic process
l-serine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
l-serine biosynthetic process
metabolic process
cellular metabolic process

Cellular Location

Cytoplasmic

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycine and Serine Metabolism
L-serine biosynthesis	Not Available	Not Available
Glycine, serine and threonine metabolism	Not Available
Dimethylglycine Dehydrogenase Deficiency		Not Available
Dihydropyrimidine Dehydrogenase Deficiency (DHPD)		Not Available

Gene Properties

Chromosome Location

Locus

7p11.2

SNPs

PSPH

Gene Sequence

>678 bp
ATGGTCTCCCACTCAGAGCTGAGGAAGCTTTTCTACTCAGCAGATGCTGTGTGTTTTGAT
GTTGACAGCACGGTCATCAGAGAAGAAGGAATCGATGAGCTAGCCAAAATCTGTGGCGTT
GAGGACGCGGTGTCAGAAATGACACGGCGAGCCATGGGCGGGGCAGTGCCTTTCAAAGCT
GCTCTCACAGAGCGCTTAGCCCTCATCCAGCCCTCCAGGGAGCAGGTGCAGAGACTCATA
GCAGAGCAACCCCCACACCTGACCCCCGGCATAAGGGAGCTGGTAAGTCGCCTACAGGAG
CGAAATGTTCAGGTTTTCCTAATATCTGGTGGCTTTAGGAGTATTGTAGAGCATGTTGCT
TCAAAGCTCAATATCCCAGCAACCAATGTATTTGCCAATAGGCTGAAATTCTACTTTAAC
GGTGAATATGCAGGTTTTGATGAGACGCAGCCAACAGCTGAATCTGGTGGAAAAGGAAAA
GTGATTAAACTTTTAAAGGAAAAATTTCATTTTAAGAAAATAATCATGATTGGAGATGGT
GCCACAGATATGGAAGCCTGTCCTCCTGCTGATGCTTTCATTGGATTTGGAGGAAATGTG
ATCAGGCAACAAGTCAAGGATAACGCCAAATGGTATATCACTGATTTTGTAGAGCTGCTG
GGAGAACTGGAAGAATAA

Protein Properties

Number of Residues

225

Molecular Weight

25007.49

Theoretical pI

5.694

Pfam Domain Function

Hydrolase (PF00702 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Phosphoserine phosphatase
MVSHSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKA
ALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVA
SKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLLKEKFHFKKIIMIGDG
ATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE

External Links

GenBank ID Protein

1890331

UniProtKB/Swiss-Prot ID

P78330

UniProtKB/Swiss-Prot Entry Name

SERB_HUMAN

PDB IDs

GenBank Gene ID

Y10275

GeneCard ID

PSPH