Identification |
HMDB Protein ID
| CDBP00747 |
Secondary Accession Numbers
| Not Available |
Name
| Transaldolase |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| TALDO1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
|
GO Classification
|
Biological Process |
pentose-phosphate shunt, non-oxidative branch |
pentose-phosphate shunt |
fructose 6-phosphate metabolic process |
energy reserve metabolic process |
glyceraldehyde-3-phosphate metabolic process |
xylulose biosynthetic process |
Cellular Component |
cytosol |
Component |
cell part |
intracellular part |
cytoplasm |
Function |
catalytic activity |
transferase activity |
transferase activity, transferring aldehyde or ketonic groups |
transaldolase activity |
Molecular Function |
monosaccharide binding |
sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity |
Process |
metabolic process |
primary metabolic process |
pentose-phosphate shunt |
carbohydrate metabolic process |
small molecule metabolic process |
alcohol metabolic process |
monosaccharide metabolic process |
hexose metabolic process |
glucose metabolic process |
glucose catabolic process |
|
Cellular Location
|
- Cytoplasm (Probable)
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Pentose Phosphate Pathway | | | Glucose-6-phosphate dehydrogenase deficiency | | Not Available | Ribose-5-phosphate isomerase deficiency | | Not Available | Transaldolase deficiency | | Not Available | Warburg Effect | | Not Available |
|
Gene Properties |
Chromosome Location
| 11 |
Locus
| 11p15.5-p15.4 |
SNPs
| TALDO1 |
Gene Sequence
|
>1014 bp
ATGTCGAGCTCACCCGTGAAGCGTCAGAGGATGGAGTCCGCGCTGGACCAGCTCAAGCAG
TTCACCACCGTGGTGGCCGACACGGGCGACTTCCACGCCATCGACGAGTACAAGCCCCAG
GATGCTACCACCAACCCGTCCCTGATCCTGGCCGCAGCACAGATGCCCGCTTACCAGGAG
CTGGTGGAGGAGGCGATTGCCTATGGCCGGAAGCTGGGCGGGTCACAAGAGGACCAGATT
AAAAATGCTATTGATAAACTTTTTGTGTTGTTTGGAGCAGAAATACTAAAGAAGATTCCG
GGCCGAGTATCCACAGAAGTAGACGCAAGGCTCTCCTTTGATAAAGATGCGATGGTGGCC
AGAGCCAGGCGGCTCATCGAGCTCTACAAGGAAGCTGGGATCAGCAAGGACCGAATTCTT
ATAAAGCTGTCATCAACCTGGGAAGGAATTCAGGCTGGAAAGGAGCTCGAGGAGCAGCAC
GGCATCCACTGCAACATGACGTTACTCTTCTCCTTCGCCCAGGCTGTGGCCTGTGCCGAG
GCGGGTGTGACCCTCATCTCCCCATTTGTTGGGCGCATCCTTGATTGGCATGTGGCAAAC
ACCGACAAGAAATCCTATGAGCCCCTGGAAGACCCTGGGGTAAAGAGTGTCACTAAAATC
TACAACTACTACAAGAAGTTTAGCTACAAAACCATTGTCATGGGCGCCTCCTTCCGCAAC
ACGGGCGAGATCAAAGCACTGGCCGGCTGTGACTTCCTCACCATCTCACCCAAGCTCCTG
GGAGAGCTGCTGCAGGACAACGCCAAGCTGGTGCCTGTGCTCTCAGCCAAGGCGGCCCAA
GCCAGTGACCTGGAAAAAATCCACCTGGATGAGAAGTCTTTCCGTTGGTTGCACAACGAG
GACCAGATGGCTGTGGAGAAGCTCTCTGACGGGATCCGCAAGTTTGCCGCTGATGCAGTG
AAGCTGGAGCGGATGCTGACAGAACGAATGTTCAATGCAGAGAATGGAAAGTAG
|
Protein Properties |
Number of Residues
| 337 |
Molecular Weight
| 37539.74 |
Theoretical pI
| 6.812 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Transaldolase
MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQE
LVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVA
RARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAE
AGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRN
TGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNE
DQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK
|
External Links |
GenBank ID Protein
| 2612879 |
UniProtKB/Swiss-Prot ID
| P37837 |
UniProtKB/Swiss-Prot Entry Name
| TALDO_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF010400 |
GeneCard ID
| TALDO1 |
GenAtlas ID
| TALDO1 |
HGNC ID
| HGNC:11559 |
References |
General References
| Not Available |