729 CDBP00728 Alcohol dehydrogenase class 4 mu/sigma chain P40394 ADH7_HUMAN true false Enzyme Homo_sapiens ADH7 386 41480.985 7.861 Involved in zinc ion binding Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism. 1AGN;1D1S;1D1T NM_000673.4 71743840 ADH7 4 4q23-q24 ADH7 HGNC:256 true hsa:131 NP_000664.2:NM_000673.4;NP_001159976.1:NM_001166504.1 Preferentially expressed in stomach. zinc ions Homodimer 2020-06-12T23:06:51Z 2020-07-28T02:25:55Z 1 1 0