<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">655</id>
  <cancdbp-id>CDBP00654</cancdbp-id>
  <name>Guanine deaminase</name>
  <uniprot-id>Q9Y2T3</uniprot-id>
  <uniprot-name>GUAD_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>GDA</gene-name>
  <num-residues type="integer">454</num-residues>
  <molecular-weight type="decimal">52836.65</molecular-weight>
  <theoretical-pi type="decimal">5.845</theoretical-pi>
  <general-function>Involved in hydrolase activity</general-function>
  <specific-function>Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia (By similarity).
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids>2UZ9;3E0L;4AQL</pdb-ids>
  <genbank-gene-id>NM_004293.3</genbank-gene-id>
  <genbank-protein-id>4758426</genbank-protein-id>
  <genecard-id>GDA</genecard-id>
  <chromosome-location>9</chromosome-location>
  <locus>9q21.13</locus>
  <geneatlas-id>GDA</geneatlas-id>
  <hgnc-id>HGNC:4212</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:9615</kegg-id>
  <meta-cyc-id>HS04276-MONOMER</meta-cyc-id>
  <ncbi-sequence-ids>NP_001229434.1:NM_001242505.2;NP_001229435.1:NM_001242506.2;NP_001229436.1:NM_001242507.2;NP_004284.1:NM_004293.4</ncbi-sequence-ids>
  <tissue-specificity></tissue-specificity>
  <cofactor>zinc ion</cofactor>
  <subunit>Homodimer
</subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:51Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:25:49Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">1</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

