Cannabis Compound Database: Showing Protein Argininosuccinate synthase (CDBP00622)

Identification Biological properties Gene properties Protein properties External links References XML Show 7 compounds

Identification

HMDB Protein ID

CDBP00622

Secondary Accession Numbers

Not Available

Name

Argininosuccinate synthase

Description

Not Available

Synonyms

Citrulline--aspartate ligase

Gene Name

ASS1

Protein Type

Enzyme

Biological Properties

General Function

Involved in argininosuccinate synthase activity

Specific Function

Not Available

GO Classification

Biological Process
cellular response to amino acid stimulus
cellular response to dexamethasone stimulus
cellular response to ammonium ion
urea cycle
cellular response to cAMP
cellular response to interferon-gamma
cellular response to oleic acid
cellular response to glucagon stimulus
cellular response to tumor necrosis factor
diaphragm development
response to growth hormone stimulus
response to mycotoxin
liver development
response to drug
response to nutrient
cellular response to lipopolysaccharide
response to zinc ion
aging
acute-phase response
kidney development
arginine biosynthetic process
argininosuccinate metabolic process
midgut development
cellular response to amine stimulus
response to estradiol stimulus
Cellular Component
cytosol
endoplasmic reticulum
nucleus
cell body fiber
perikaryon
lysosome
mitochondrial outer membrane
Function
adenyl ribonucleotide binding
atp binding
ligase activity
argininosuccinate synthase activity
ligase activity, forming carbon-nitrogen bonds
binding
catalytic activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
Molecular Function
argininosuccinate synthase activity
toxin binding
ATP binding
Process
arginine biosynthetic process
metabolic process
arginine metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Arginine and Proline Metabolism
Aspartate Metabolism
Urea Cycle
L-arginine biosynthesis	Not Available	Not Available
Alanine, aspartate and glutamate metabolism	Not Available

Gene Properties

Chromosome Location

Locus

9q34.1

SNPs

ASS1

Gene Sequence

>1239 bp
ATGTCCAGCAAAGGCTCCGTGGTTCTGGCCTACAGTGGCGGCCTGGACACCTCGTGCATC
CTCGTGTGGCTGAAGGAACAAGGCTATGACGTCATTGCCTATCTGGCCAACATTGGCCAG
AAGGAAGACTTCGAGGAAGCCAGGAAGAAGGCACTGAAGCTTGGGGCCAAAAAGGTGTTC
ATTGAGGATGTCAGCAGGGAGTTTGTGGAGGAGTTCATCTGGCCGGCCATCCAGTCCAGC
GCACTGTATGAGGACCGCTACCTCCTGGGCACCTCTCTTGCCAGGCCCTGCATCGCCCGC
AAACAAGTGGAAATCGCCCAGCGGGAGGGGGCCAAGTATGTGTCCCACGGCGCCACAGGA
AAGGGGAACGATCAGGTCCGGTTTGAGCTCAGCTGCTACTCACTGGCCCCCCAGATAAAG
GTCATTGCTCCCTGGAGGATGCCTGAATTCTACAACCGGTTCAAGGGCCGCAATGACCTG
ATGGAGTACGCAAAGCAACACGGGATTCCCATCCCGGTCACTCCCAAGAACCCGTGGAGC
ATGGATGAGAACCTCATGCACATCAGCTACGAGGCTGGAATCCTGGAGAACCCCAAGAAC
CAAGCGCCTCCAGGTCTCTACACGAAGACCCAGGACCCAGCCAAAGCCCCCAACACCCCT
GACATTCTCGAGATCGAGTTCAAAAAAGGGGTCCCTGTGAAGGTGACCAACGTCAAGGAT
GGCACCACCCACCAGACCTCCTTGGAGCTCTTCATGTACCTGAACGAAGTCGCGGGCAAG
CATGGCGTGGGCCGTATTGACATCGTGGAGAACCGCTTCATTGGAATGAAGTCCCGAGGT
ATCTACGAGACCCCAGCAGGCACCATCCTTTACCATGCTCATTTAGACATCGAGGCCTTC
ACCATGGACCGGGAAGTGCGCAAAATCAAACAAGGCCTGGGCTTGAAATTTGCTGAGCTG
GTGTATACCGGTTTACGGCCTAGCCCTGAGTGTGAATTTGTCCGCCACTGCATCGCCAAG
TCCCAGGAGCGAGTGGAAGGGAAAGTGCAGGTGTCCGTCCTCAAGGGCCAGGTGTACATC
CTCGGCCGGGAGTCCCCACTGTCTCTCTACAATGAGGAGCTGGTGAGCATGAACGTGCAG
GGTGATTATGAGCCAACTGATGCCACCGGGTTCATCAACATCAATTCCCTCAGGCTGAAG
GAATATCATCGTCTCCAGAGCAAGGTCACTGCCAAATAG

Protein Properties

Number of Residues

412

Molecular Weight

46530.055

Theoretical pI

8.022

Pfam Domain Function

Arginosuc_synth (PF00764 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Argininosuccinate synthase
MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF
IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG
KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS
MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD
GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF
TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI
LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK

External Links

GenBank ID Protein

28872

UniProtKB/Swiss-Prot ID

P00966

UniProtKB/Swiss-Prot Entry Name

ASSY_HUMAN

PDB IDs