Cannabis Compound Database: Showing Protein Adenosine kinase (CDBP00606)

Identification Biological properties Gene properties Protein properties External links References XML Show 5 compounds

Identification

HMDB Protein ID

CDBP00606

Secondary Accession Numbers

Not Available

Name

Adenosine kinase

Description

Not Available

Synonyms

AK
Adenosine 5'-phosphotransferase

Gene Name

ADK

Protein Type

Enzyme

Biological Properties

General Function

Involved in adenosine kinase activity

Specific Function

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

GO Classification

Biological Process
adenosine metabolic process
purine nucleobase metabolic process
AMP salvage
dATP biosynthetic process
positive regulation of T cell proliferation
purine ribonucleoside salvage
purine-containing compound salvage
Cellular Component
cytosol
nucleus
Function
nucleobase, nucleoside, nucleotide kinase activity
nucleoside kinase activity
adenosine kinase activity
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
Molecular Function
metal ion binding
adenosine kinase activity
phosphotransferase activity, alcohol group as acceptor
ATP binding
Process
metabolic process
biosynthetic process
cellular biosynthetic process
heterocycle biosynthetic process
purine salvage
purine ribonucleoside salvage

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
AMP biosynthesis via salvage pathway	Not Available	Not Available
Mercaptopurine Action Pathway		Not Available
Mercaptopurine Metabolism Pathway		Not Available
Thioguanine Action Pathway		Not Available
Azathioprine Action Pathway		Not Available

Gene Properties

Chromosome Location

Locus

10q11-q24

SNPs

ADK

Gene Sequence

>1089 bp
ATGGCAGCTGCTGAGGAGGAGCCGAAGCCCAAAAAGCTGAAGGTGGAGGCGCCGCAAGCG
CTGAGAGAAAATATTCTCTTTGGAATGGGAAATCCTCTGCTTGACATCTCTGCTGTAGTG
GACAAAGATTTCCTTGATAAGTATTCTCTGAAACCAAATGACCAAATCTTGGCTGAAGAC
AAACACAAGGAACTGTTTGATGAACTTGTGAAAAAATTCAAAGTCGAATATCATGCTGGT
GGCTCTACCCAGAATTCAATTAAAGTGGCTCAGTGGATGATTCAACAGCCACACAAAGCA
GCAACATTTTTTGGATGCATTGGGATAGATAAATTTGGGGAGATCCTGAAGAGAAAAGCT
GCTGAAGCCCATGTGGATGCTCATTACTACGAGCAGAATGAGCAGCCAACAGGAACTTGT
GCTGCATGCATCACTGGTGACAACAGGTCCCTCATAGCTAATCTTGCTGCTGCCAATTGT
TATAAAAAGGAAAAACATCTTGATCTGGAGAAAAACTGGATGTTGGTAGAAAAAGCAAGA
GTTTGTTATATAGCAGGCTTTTTTCTTACAGTTTCCCCAGAGTCAGTATTAAAGGTGGCT
CACCATGCTTCTGAAAACAACAGGATTTTCACTTTGAATCTATCTGCACCGTTTATTAGC
CAGTTCTACAAGGAATCATTGATGAAAGTTATGCCTTATGTTGATATACTTTTTGGAAAT
GAGACAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAG
ATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATC
TTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCT
GTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTT
GGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGC
CACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGAC
TTCCACTGA

Protein Properties

Number of Residues

362

Molecular Weight

38702.93

Theoretical pI

6.688

Pfam Domain Function

PfkB (PF00294 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Adenosine kinase
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH

External Links

GenBank ID Protein

32484975

UniProtKB/Swiss-Prot ID

P55263

UniProtKB/Swiss-Prot Entry Name

ADK_HUMAN

PDB IDs

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Not Available