Cannabis Compound Database: Showing Protein Tryptophan--tRNA ligase, mitochondrial (CDBP00593)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00593

Secondary Accession Numbers

Not Available

Name

Tryptophan--tRNA ligase, mitochondrial

Description

Not Available

Synonyms

(Mt)TrpRS
TrpRS
Tryptophan--tRNA ligase
Tryptophanyl-tRNA synthetase

Gene Name

WARS2

Protein Type

Enzyme

Biological Properties

General Function

Involved in nucleotide binding

Specific Function

Not Available

GO Classification

Biological Process
vasculogenesis
tRNA aminoacylation for protein translation
tryptophanyl-tRNA aminoacylation
Cellular Component
mitochondrial matrix
Component
cell part
intracellular part
cytoplasm
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
tryptophan-trna ligase activity
ligase activity
ligase activity, forming carbon-oxygen bonds
ligase activity, forming aminoacyl-trna and related compounds
aminoacyl-trna ligase activity
binding
nucleotide binding
catalytic activity
nucleoside binding
purine nucleoside binding
Molecular Function
ATP binding
tryptophan-tRNA ligase activity
Process
cellular macromolecule biosynthetic process
translation
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
tryptophanyl-trna aminoacylation
biosynthetic process
rna metabolic process
ncrna metabolic process
trna metabolic process
trna aminoacylation
trna aminoacylation for protein translation
macromolecule biosynthetic process

Cellular Location

Mitochondrion matrix

Pathways

Name	SMPDB/Pathwhiz	KEGG
Tryptophan Metabolism
Aminoacyl-tRNA biosynthesis	Not Available

Gene Properties

Chromosome Location

Locus

1p12

SNPs

WARS2

Gene Sequence

>1083 bp
ATGGCGCTGCACTCAATGCGGAAAGCGCGTGAGCGCTGGAGCTTCATCCGGGCACTTCAT
AAGGGATCCGCAGCTGCTCCCGCTCTCCAGAAAGACAGCAAGAAGCGAGTATTTTCCGGC
ATTCAACCTACAGGAATCCTCCACCTGGGCAATTACCTGGGAGCCATTGAGAGCTGGGTG
AGGTTACAGGATGAATATGACTCTGTATTATACAGCATTGTTGACCTCCACTCCATTACT
GTCCCCCAAGACCCAGCTGTCCTTCGGCAGAGCATCCTGGACATGACTGCTGTTCTTCTT
GCCTGTGGCATAAACCCGGAAAAAAGCATCCTTTTCCAACAATCTCAGGTGTCTGAACAC
ACACAATTAAGTTGGATCCTTTCCTGCATGGTCAGACTACCTCGATTACAACATTTACAT
CAGTGGAAGGCAAAGACTACCAAGCAGAAGCACGATGGCACGGTGGGCCTGCTCACATAC
CCAGTACTCCAGGCAGCCGACATTCTGTTGTACAAGTCCACACACGTTCCTGTTGGGGAG
GATCAAGTCCAGCACATGGAACTAGTTCAGGATCTAGCACAAGGTTTCAACAAGAAGTAT
GGGGAGTTCTTTCCAGTGCCCGAGTCCATTCTCACATCCATGAAGAAGGTAAAATCCCTA
CGTGATCCTTCTGCCAAAATGTCGAAATCAGACCCTGACAAACTGGCCACCGTCCGAATA
ACAGACAGCCCAGAGGAGATAGTGCAGAAATTCCGCAAGGCTGTGACAGACTTCACCTCG
GAGGTCACCTATGACCCGGCTGGCCGCGCTGGCGTGTCCAACATAGTGGCGGTGCATGCC
GCGGTGACGGGGCTCTCCGTGGAGGAAGTGGTGCGCCGCAGCGCGGGCATGAACACTGCT
CGCTACAAGCTGGCCGTGGCAGATGCTGTGATTGAGAAGTTTGCCCCAATTAAGCGTGAA
ATTGAAAAACTGAAGCTGGACAAGGACCATTTAGAGAAGGTTTTACAAATTGGATCAGCA
AAAGCCAAAGAATTAGCATACACTGTGTGCCAGGAGGTGAAGAAATTGGTGGGTTTTCTA
TAG

Protein Properties

Number of Residues

360

Molecular Weight

40146.265

Theoretical pI

9.273

Pfam Domain Function

tRNA-synt_1b (PF00579 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Tryptophanyl-tRNA synthetase, mitochondrial
MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV
RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH
TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE
DQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRI
TDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTA
RYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL

External Links

GenBank ID Protein

6572289

UniProtKB/Swiss-Prot ID

Q9UGM6

UniProtKB/Swiss-Prot Entry Name

SYWM_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AJ242739

GeneCard ID