<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">590</id>
  <cancdbp-id>CDBP00589</cancdbp-id>
  <name>Long-chain-fatty-acid--CoA ligase 6</name>
  <uniprot-id>Q9UKU0</uniprot-id>
  <uniprot-name>ACSL6_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>ACSL6</gene-name>
  <num-residues type="integer">697</num-residues>
  <molecular-weight type="decimal">80609.765</molecular-weight>
  <theoretical-pi type="decimal">7.29</theoretical-pi>
  <general-function>Involved in catalytic activity</general-function>
  <specific-function>Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids></pdb-ids>
  <genbank-gene-id>AF129166</genbank-gene-id>
  <genbank-protein-id>5702202</genbank-protein-id>
  <genecard-id>ACSL6</genecard-id>
  <chromosome-location>5</chromosome-location>
  <locus>5q31</locus>
  <geneatlas-id>ACSL6</geneatlas-id>
  <hgnc-id>HGNC:16496</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:23305</kegg-id>
  <meta-cyc-id></meta-cyc-id>
  <ncbi-sequence-ids>NP_001009185.1:NM_001009185.2;NP_001192176.1:NM_001205247.1;NP_001192177.1:NM_001205248.1;NP_001192179.1:NM_001205250.1;NP_001192180.1:NM_001205251.1;NP_056071.2:NM_015256.3</ncbi-sequence-ids>
  <tissue-specificity>Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
</tissue-specificity>
  <cofactor>Magnesium</cofactor>
  <subunit></subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:50Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:25:43Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">0</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

