Cannabis Compound Database: Showing Protein AMP deaminase 2 (CDBP00566)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00566

Secondary Accession Numbers

Not Available

Name

AMP deaminase 2

Description

Not Available

Synonyms

AMP deaminase isoform L

Gene Name

AMPD2

Protein Type

Enzyme

Biological Properties

General Function

Involved in deaminase activity

Specific Function

AMP deaminase plays a critical role in energy metabolism.

GO Classification

Biological Process
purine nucleobase metabolic process
purine-containing compound salvage
IMP salvage
purine nucleotide metabolic process
Cellular Component
cytosol
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
amp deaminase activity
deaminase activity
Molecular Function
metal ion binding
AMP deaminase activity
Process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
cellular aromatic compound metabolic process
purine nucleoside monophosphate biosynthetic process
purine ribonucleoside monophosphate biosynthetic process
purine base metabolic process
cellular metabolic process
nucleobase metabolic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process

Cellular Location

Cytoplasmic

Pathways

Name	SMPDB/Pathwhiz	KEGG
IMP biosynthesis via salvage pathway	Not Available	Not Available

Gene Properties

Chromosome Location

Locus

1p13.3

SNPs

AMPD2

Gene Sequence

>2640 bp
ATGAGAAATCGTGGCCAGGGCCTCTTCCGCCTGCGGAGCCGCTGCTTCCTGCATCAGTCA
CTCCCGCTGGGGGCGGGGCGGAGGAAGGGGTTGGATGTGGCAGAGCCAGGCCCCAGCCGG
TGCCGCTCAGACTCCCCCGCTGTCGCCGCCGTGGTCCCAGCCATGGCATCCTATCCATCT
GGCTCTGGCAAGCCCAAGGCCAAATATCCCTTTAAGAAGCGGGCCAGCCTGCAGGCCTCC
ACTGCAGCTCCAGAGGCTCGGGGTGGTCTGGGGGCCCCTCCGCTGCAGTCTGCCCGATCC
CTGCCGGGCCCCGCCCCCTGCCTCAAGCACTTCCCGCTCGACCTGCGCACGTCTATGGAT
GGCAAATGCAAGGAGATCGCCGAGGAGCTGTTCACCCGCTCACTGGCTGAGAGCGAGCTC
CGTAGTGCCCCGTATGAGTTCCCCGAGGAGAGCCCCATTGAACAGCTGGAGGAGCGGCGG
CAGCGGCTGGAGCGGCAGATCAGCCAGGATGTCAAGCTGGAGCCAGACATCCTGCTTCGG
GCCAAGCAAGATTTCCTGAAGACGGACAGTGACTCGGACCTACAGCTCTACAAGGAACAG
GGTGAGGGGCAGGGTGACCGGAGCCTGCGGGAGCGTGATGTGCTGGAACGGGAGTTTCAG
CGGGTCACCATCTCTGGGGAGGAGAAGTGTGGGGTGCCGTTCACAGACCTGCTGGATGCA
GCCAAGAGTGTGGTGCGGGCGCTCTTCATCCGGGAGAAGTACATGGCCCTGTCCCTGCAG
AGCTTCTGCCCCACCACCCGCCGCTACCTGCAGCAGCTGGCTGAAAAGCCTCTGGAGACC
CGGACCTATGAACAGGGCCCCGACACCCCTGTGTCTGCTGATGCCCCGGTGCACCCCCCT
GCGCTGGAGCAGCACCCGTATGAGCACTGTGAGCCAAGCACCATGCCTGGGGACCTGGGC
TTGGGTCTGCGCATGGTGCGGGGTGTGGTGCACGTCTACACCCGCAGGGAACCCGACGAG
CATTGCTCAGAGGTGGAGCTGCCATACCCTGACCTGCAGGAATTTGTGGCTGACGTCAAT
GTGCTGATGGCCCTGATTATCAATGGCCCCATAAAGTCATTCTGCTACCGCCGGCTGCAG
TACCTGAGCTCCAAGTTCCAGATGCATGTGCTACTCAATGAGATGAAGGAGCTGGCCGCC
CAGAAGAAAGTGCCACACCGAGATTTCTACAACATCCGCAAGGTGGACACCCACATCCAT
GCCTCGTCCTGCATGAACCAGAAGCATCTGCTGCGCTTCATCAAGCGGGCAATGAAGCGG
CACCTGGAGGAGATCGTGCACGTGGAGCAGGGCCGTGAACAGACGCTGCGGGAGGTCTTT
GAGAGCATGAATCTCACGGCCTACGACCTGAGTGTGGACACGCTGGATGTGCATGCGGAC
AGGAACACTTTCCATCGCTTTGACAAGTTTAATGCCAAATACAACCCTATTGGGGAGTCC
GTCCTCCGAGAGATCTTCATCAAGACGGACAACAGGGTATCTGGGAAGTACTTTGCTCAC
ATCATCAAGGAGGTGATGTCAGACCTGGAGGAGAGCAAATACCAGAATGCAGAGCTGCGG
CTCTCCATTTACGGGCGCTCGAGGGATGAGTGGGACAAGCTGGCGCGCTGGGCCGTCATG
CACCGCGTGCACTCCCCCAACGTGCGCTGGCTGGTGCAGGTGCCCCGCCTCTTTGATGTG
TACCGTACCAAGGGCCAGCTGGCCAACTTCCAGGAGATGCTGGAGAACATCTTCCTGCCA
CTGTTCGAGGCCACTGTGCACCCTGCCAGCCACCCGGAACTGCATCTCTTCTTAGAGCAC
GTGGATGGTTTTGACAGCGTGGATGATGAGTCCAAGCCTGAAAACCATGTCTTCAACCTG
GAGAGCCCCCTGCCTGAGGCGTGGGTGGAGGAGGACAACCCACCCTATGCCTACTACCTG
TACTACACCTTTGCCAACATGGCCATGTTGAACCACCTGCGCAGGCAGAGGGGCTTCCAC
ACGTTTGTGCTGAGGCCACACTGTGGGGAGGCTGGGCCCATCCACCACCTGGTGTCAGCC
TTCATGCTGGCTGAGAACATTTCCCACGGGCTCCTTCTGCGCAAGGCCCCCGTCCTGCAG
TACCTGTACTACCTGGCCCAGATCGGCATCGCCATGTCTCCGCTCAGCAACAACAGCCTC
TTCCTCAGCTATCACCGGAATCCGCTACCGGAGTACCTGTCCCGCGGCCTCATGGTCTCC
CTGTCCACTGATGATCCCTTGCAGTTCCACTTCACCAAGGAGCCGCTGATGGAGGAGTAC
AGCATCGCCACCCAGGTGTGGAAGCTCAGCTCCTGCGATATGTGTGAGCTGGCCCGCAAC
AGCGTGCTCATGAGCGGCTTCTCGCACAAGGTAAAGAGCCACTGGCTGGGACCCAACTAT
ACCAAGGAAGGCCCTGAGGGGAATGACATCCGCCGGACCAATGTGCCAGACATCCGCGTG
GGCTACCGCTACGAGACCCTGTGCCAGGAGCTGGCGCTCATCACGCAGGCAGTCCAGAGT
GAGATGCTGGAGACCATTCCAGAGGAGGCGGGTATCACCATGAGCCCAGGGCCTCAATGA

Protein Properties

Number of Residues

879

Molecular Weight

100686.95

Theoretical pI

6.933

Pfam Domain Function

A_deaminase (PF00962 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>AMP deaminase 2
MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPS
GSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMD
GKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLR
AKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDA
AKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPP
ALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVN
VLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIH
ASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHAD
RNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELR
LSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLP
LFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYL
YYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQ
YLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEY
SIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRV
GYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ

External Links

GenBank ID Protein

21264318

UniProtKB/Swiss-Prot ID

Q01433

UniProtKB/Swiss-Prot Entry Name

AMPD2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_004037.6

GeneCard ID