Showing Protein Platelet-activating factor acetylhydrolase IB subunit beta (CDBP00504)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP00504
Secondary Accession Numbers Not Available
Name Platelet-activating factor acetylhydrolase IB subunit beta
Description Not Available
Synonyms
  1. PAF acetylhydrolase 30 kDa subunit
  2. PAF-AH 30 kDa subunit
  3. PAF-AH subunit beta
  4. PAFAH subunit beta
Gene Name PAFAH1B2
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity
Specific Function Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.
GO Classification
Biological Process
spermatogenesis
lipid catabolic process
positive regulation of macroautophagy
brain development
lipid metabolic process
Cellular Component
cytosol
cytoplasm
nucleolus
plasma membrane
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
Molecular Function
1-alkyl-2-acetylglycerophosphocholine esterase activity
Process
metabolic process
primary metabolic process
lipid metabolic process
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 11
Locus 11q23
SNPs PAFAH1B2
Gene Sequence 
>690 bp
ATGAGCCAAGGAGACTCAAACCCAGCAGCTATTCCGCATGCAGCAGAAGATATTCAAGGA
GATGACCGATGGATGTCTCAGCACAACAGATTTGTTTTGGACTGTAAAGACAAAGAGCCT
GATGTACTGTTCGTGGGAGACTCCATGGTGCAGTTAATGCAGCAATATGAGATATGGCGA
GAGCTTTTTTCCCCACTTCATGCACTGAATTTTGGAATTGGGGGAGATACAACAAGACAT
GTTTTGTGGAGACTAAAGAATGGAGAACTGGAGAATATTAAGCCTAAGGTCATTGTTGTC
TGGGTAGGAACAAATAACCACGAAAATACAGCAGAAGAAGTAGCAGGTGGGATCGAGGCC
ATTGTACAACTTATCAACACAAGGCAGCCACAGGCCAAAATCATTGTATTGGGTTTGTTA
CCTCGAGGTGAGAAACCCAATCCTTTGAGGCAAAAGAACGCCAAGGTGAACCAACTCCTC
AAGGTTTCGCTGCCGAAGCTTGCCAACGTGCAGCTCCTGGATACCGACGGGGGTTTTGTG
CACTCGGACGGTGCCATCTCCTGCCACGACATGTTTGATTTTCTGCATCTGACAGGAGGG
GGCTATGCAAAGATCTGCAAACCCCTGCATGAACTGATCATGCAGTTGTTGGAGGAAACA
CCTGAGGAGAAACAAACCACCATTGCCTGA
Protein Properties
Number of Residues 229
Molecular Weight 22733.715
Theoretical pI 6.046
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Platelet-activating factor acetylhydrolase IB subunit beta
MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
GenBank ID Protein 12653259
UniProtKB/Swiss-Prot ID P68402
UniProtKB/Swiss-Prot Entry Name PA1B2_HUMAN
PDB IDs
GenBank Gene ID BC000398
GeneCard ID PAFAH1B2
GenAtlas ID PAFAH1B2
HGNC ID HGNC:8575
References
General References Not Available