Identification |
HMDB Protein ID
| CDBP00502 |
Secondary Accession Numbers
| Not Available |
Name
| Platelet-activating factor acetylhydrolase IB subunit gamma |
Description
| Not Available |
Synonyms
|
- PAF acetylhydrolase 29 kDa subunit
- PAF-AH 29 kDa subunit
- PAF-AH subunit gamma
- PAFAH subunit gamma
|
Gene Name
| PAFAH1B3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in hydrolase activity |
Specific Function
| Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
|
GO Classification
|
Biological Process |
spermatogenesis |
lipid catabolic process |
nervous system development |
brain development |
lipid metabolic process |
Cellular Component |
cytosol |
Function |
catalytic activity |
hydrolase activity |
Molecular Function |
platelet-activating factor acetyltransferase activity |
1-alkyl-2-acetylglycerophosphocholine esterase activity |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Ether lipid metabolism | Not Available | |
|
Gene Properties |
Chromosome Location
| 19 |
Locus
| 19q13.1 |
SNPs
| PAFAH1B3 |
Gene Sequence
|
>696 bp
ATGAGTGGAGAGGAGAACCCAGCCAGCAAGCCCACGCCGGTGCAGGACGTACAGGGCGAC
GGGCGCTGGATGTCCCTGCACCATCGGTTCGTGGCTGACAGCAAAGATAAGGAACCCGAA
GTCGTCTTCATCGGGGACTCCTTGGTCCAGCTCATGCACCAGTGCGAGATCTGGCGCGAG
CTCTTCTCTCCTCTGCATGCACTTAACTTTGGCATTGGTGGTGACGGCACACAGCATGTA
CTGTGGCGGCTGGAGAATGGGGAGCTGGAACACATCCGGCCCAAGATTGTGGTGGTCTGG
GTGGGCACCAACAACCACGGACACACAGCAGAGCAGGTGACTGGTGGCATCAAGGCCATT
GTGCAACTGGTGAATGAGCGACAGCCCCAGGCCCGGGTTGTGGTGCTGGGCCTGCTTCCG
CGAGGCCAACATCCCAACCCACTTCGGGAGAAGAACCGACAGGTGAACGAGCTGGTACGG
GCGGCACTGGCTGGCCACCCTCGGGCCCACTTCCTAGATGCCGACCCTGGCTTTGTGCAC
TCAGATGGCACCATCAGCCATCATGACATGTATGATTACCTGCATCTGAGCCGCCTGGGC
TACACACCTGTTTGCCGGGCTCTGCACTCCCTGCTTCTGCGTCTGCTGGCCCAAGACCAG
GGCCAAGGTGCTCCCCTGCTGGAGCCCGCACCCTAA
|
Protein Properties |
Number of Residues
| 231 |
Molecular Weight
| 25734.13 |
Theoretical pI
| 6.84 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Platelet-activating factor acetylhydrolase IB subunit gamma
MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q15102 |
UniProtKB/Swiss-Prot Entry Name
| PA1B3_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| D63391 |
GeneCard ID
| PAFAH1B3 |
GenAtlas ID
| PAFAH1B3 |
HGNC ID
| HGNC:8576 |
References |
General References
| Not Available |