Identification
HMDB Protein ID CDBP00502
Secondary Accession Numbers Not Available
Name Platelet-activating factor acetylhydrolase IB subunit gamma
Description Not Available
Synonyms
  1. PAF acetylhydrolase 29 kDa subunit
  2. PAF-AH 29 kDa subunit
  3. PAF-AH subunit gamma
  4. PAFAH subunit gamma
Gene Name PAFAH1B3
Protein Type Enzyme
Biological Properties
General Function Involved in hydrolase activity
Specific Function Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
GO Classification
Biological Process
spermatogenesis
lipid catabolic process
nervous system development
brain development
lipid metabolic process
Cellular Component
cytosol
Function
catalytic activity
hydrolase activity
Molecular Function
platelet-activating factor acetyltransferase activity
1-alkyl-2-acetylglycerophosphocholine esterase activity
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 19
Locus 19q13.1
SNPs PAFAH1B3
Gene Sequence
>696 bp
ATGAGTGGAGAGGAGAACCCAGCCAGCAAGCCCACGCCGGTGCAGGACGTACAGGGCGAC
GGGCGCTGGATGTCCCTGCACCATCGGTTCGTGGCTGACAGCAAAGATAAGGAACCCGAA
GTCGTCTTCATCGGGGACTCCTTGGTCCAGCTCATGCACCAGTGCGAGATCTGGCGCGAG
CTCTTCTCTCCTCTGCATGCACTTAACTTTGGCATTGGTGGTGACGGCACACAGCATGTA
CTGTGGCGGCTGGAGAATGGGGAGCTGGAACACATCCGGCCCAAGATTGTGGTGGTCTGG
GTGGGCACCAACAACCACGGACACACAGCAGAGCAGGTGACTGGTGGCATCAAGGCCATT
GTGCAACTGGTGAATGAGCGACAGCCCCAGGCCCGGGTTGTGGTGCTGGGCCTGCTTCCG
CGAGGCCAACATCCCAACCCACTTCGGGAGAAGAACCGACAGGTGAACGAGCTGGTACGG
GCGGCACTGGCTGGCCACCCTCGGGCCCACTTCCTAGATGCCGACCCTGGCTTTGTGCAC
TCAGATGGCACCATCAGCCATCATGACATGTATGATTACCTGCATCTGAGCCGCCTGGGC
TACACACCTGTTTGCCGGGCTCTGCACTCCCTGCTTCTGCGTCTGCTGGCCCAAGACCAG
GGCCAAGGTGCTCCCCTGCTGGAGCCCGCACCCTAA
Protein Properties
Number of Residues 231
Molecular Weight 25734.13
Theoretical pI 6.84
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Platelet-activating factor acetylhydrolase IB subunit gamma
MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q15102
UniProtKB/Swiss-Prot Entry Name PA1B3_HUMAN
PDB IDs Not Available
GenBank Gene ID D63391
GeneCard ID PAFAH1B3
GenAtlas ID PAFAH1B3
HGNC ID HGNC:8576
References
General References Not Available