Cannabis Compound Database: Showing Protein Non-specific lipid-transfer protein (CDBP00431)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00431

Secondary Accession Numbers

Not Available

Name

Non-specific lipid-transfer protein

Description

Not Available

Synonyms

NSL-TP
Propanoyl-CoA C-acyltransferase
SCP-2
SCP-X
SCP-chi
SCPX
Sterol carrier protein 2
Sterol carrier protein X

Gene Name

SCP2

Protein Type

Enzyme

Biological Properties

General Function

Involved in oxidoreductase activity

Specific Function

Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.

GO Classification

Biological Process
progesterone biosynthetic process
alpha-linolenic acid metabolic process
fatty acid beta-oxidation using acyl-CoA oxidase
lipid transport
inositol trisphosphate biosynthetic process
lipid hydroperoxide transport
peroxisome organization
positive regulation of intracellular cholesterol transport
positive regulation of steroid metabolic process
protein localization to plasma membrane
bile acid biosynthetic process
Cellular Component
cytoplasm
mitochondrion
nucleus
peroxisomal matrix
protein complex
Function
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
oxidoreductase activity
steroid binding
sterol binding
lipid binding
binding
Molecular Function
cholesterol binding
long-chain fatty acyl-CoA binding
oleic acid binding
phosphatidylinositol transporter activity
propanoyl-CoA C-acyltransferase activity
transferase activity, transferring acyl groups other than amino-acyl groups
sterol binding
Process
metabolic process

Cellular Location

Isoform SCP2:Mitochondrion (Probable)

Pathways

Name	SMPDB/Pathwhiz	KEGG
Primary bile acid biosynthesis	Not Available
PPAR signaling pathway	Not Available
Peroxisome	Not Available
Bile Acid Biosynthesis
Congenital Bile Acid Synthesis Defect Type II		Not Available

Gene Properties

Chromosome Location

Locus

1p32

SNPs

SCP2

Gene Sequence

>1644 bp
ATGTCCTCTTCCCCGTGGGAGCCTGCGACCCTGCGCCGGGTGTTCGTGGTGGGGGTTGGC
ATGACCAAGTTTGTGAAGCCTGGAGCTGAGAATTCAAGAGACTACCCTGACTTGGCAGAA
GAAGCAGGCAAGAAGGCTTTAGCTGATGCACAGATCCCTTATTCAGCAGTGGACCAGGCA
TGTGTTGGCTATGTTTTTGGTGACTCTACCTGTGGGCAGAGGGCTATCTATCACAGTTTG
GGAATGACTGGAATTCCTATAATCAATGTCAACAATAACTGTGCTACTGGTTCTACTGCT
TTGTTTATGGCCCGCCAGCTGATTCAGGGTGGTGTGGCAGAATGTGTCTTGGCTCTTGGG
TTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACT
GATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCT
CAGATGTTTGGGTATGCTGGAAAAGAACATATGGAAAAATATGGAACAAAAATTGAACAC
TTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTC
CAAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACT
ATCTTACAATGTTGTCCCACTTCAGATGGTGCTGCAGCAGCAATTTTGGCCAGTGAAGCA
TTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATG
ACTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATG
AGTAAAGAAGCTGCAAGAAAATGCTATGAGAAATCTGGCCTGACACCAAATGATATTGAC
GTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTGACTTATGAAGCACTCGGA
CTCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGA
AAGTGGGTCATAAATCCTAGTGGTGGACTGATTTCAAAGGGACACCCACTAGGCGCTACA
GGTCTTGCTCAGTGTGCAGAACTCTGCTGGCAGCTGAGAGGGGAAGCCGGAAAGAGGCAA
GTTCCTGGTGCAAAGGTGGCTCTGCAGCATAATTTAGGCATTGGAGGAGCTGTGGTTGTA
ACACTCTACAAGATGGGTTTTCCGGAAGCCGCCAGTTCTTTTAGAACTCATCAAATTGAA
GCTGTTCCAACCAGCTCTGCAAGTGATGGATTTAAGGCAAATCTTGTTTTTAAGGAGATT
GAGAAGAAACTTGAAGAGGAAGGGGAACAGTTTGTGAAGAAAATCGGTGGTATTTTTGCC
TTCAAGGTGAAAGATGGCCCTGGGGGTAAAGAGGCCACCTGGGTGGTGGATGTGAAGAAT
GGCAAAGGATCAGTGCTTCCTAACTCAGATAAGAAGGCTGACTGCACAATCACAATGGCT
GACTCAGACTTCCTGGCTTTAATGACTGGTAAAATGAATCCTCAGTCGGCCTTCTTTCAA
GGCAAATTGAAAATCACTGGCAACATGGGTCTCGCTATGAAGTTACAAAATCTTCAGCTT
CAGCCAGGCAACGCTAAGCTCTGA

Protein Properties

Number of Residues

547

Molecular Weight

34974.505

Theoretical pI

5.658

Pfam Domain Function

Thiolase_C (PF02803 )
Thiolase_N (PF00108 )
SCP2 (PF02036 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Non-specific lipid-transfer protein
MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA
CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG
FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH
FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA
FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID
VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT
GLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIE
AVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKN
GKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQL
QPGNAKL

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

P22307

UniProtKB/Swiss-Prot Entry Name

NLTP_HUMAN

PDB IDs