Identification |
HMDB Protein ID
| CDBP00417 |
Secondary Accession Numbers
| Not Available |
Name
| Guanidinoacetate N-methyltransferase |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| GAMT |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in guanidinoacetate N-methyltransferase activity |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
spermatogenesis |
organ morphogenesis |
cellular nitrogen compound metabolic process |
muscle contraction |
S-adenosylhomocysteine metabolic process |
creatine biosynthetic process |
regulation of multicellular organism growth |
S-adenosylmethionine metabolic process |
Cellular Component |
cytosol |
Molecular Function |
guanidinoacetate N-methyltransferase activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Arginine and Proline Metabolism | ![Thumb](https://smpdb.ca/super_pathway_visualizations/PW000010/thumb) ![Thumb?image type=greyscale](https://smpdb.ca/super_pathway_visualizations/PW000010/thumb?image_type=greyscale) ![Thumb?image type=simple](https://smpdb.ca/super_pathway_visualizations/PW000010/thumb?image_type=simple) | ![Map00330](https://www.genome.jp/kegg/misc/thumbnail/map00330.gif) | Glycine and Serine Metabolism | ![Thumb](https://smpdb.ca/super_pathway_visualizations/PW000157/thumb) ![Thumb?image type=greyscale](https://smpdb.ca/super_pathway_visualizations/PW000157/thumb?image_type=greyscale) ![Thumb?image type=simple](https://smpdb.ca/super_pathway_visualizations/PW000157/thumb?image_type=simple) | ![Map00260](https://www.genome.jp/kegg/misc/thumbnail/map00260.gif) | creatine biosynthesis | Not Available | Not Available | Glycine, serine and threonine metabolism | Not Available | ![Map00260](https://www.genome.jp/kegg/misc/thumbnail/map00260.gif) | Prolidase Deficiency (PD) | ![Thumb](https://smpdb.ca/super_pathway_visualizations/PW000083/thumb) ![Thumb?image type=greyscale](https://smpdb.ca/super_pathway_visualizations/PW000083/thumb?image_type=greyscale) ![Thumb?image type=simple](https://smpdb.ca/super_pathway_visualizations/PW000083/thumb?image_type=simple) | Not Available |
|
Gene Properties |
Chromosome Location
| 19 |
Locus
| 19p13.3 |
SNPs
| GAMT |
Gene Sequence
|
>711 bp
ATGAGCGCCCCCAGCGCGACCCCCATCTTCGCGCCCGGCGAGAACTGCAGCCCCGCGTGG
GGGGCGGCGCCCGCGGCCTACGACGCAGCGGACACGCACCTGCGCATCCTGGGCAAGCCG
GTGATGGAGCGCTGGGAGACCCCCTATATGCACGCGCTGGCCGCCGCCGCCTCCTCCAAA
GGGGGCCGGGTCCTGGAGGTGGGCTTTGGCATGGCCATCGCAGCGTCAAAGGTGCAGGAG
GCGCCCATTGATGAGCATTGGATCATCGAGTGCAATGACGGCGTCTTCCAGCGGCTCCGG
GACTGGGCCCCACGGCAGACACACAAGGTCATCCCCTTGAAAGGCCTGTGGGAGGATGTG
GCACCCACCCTGCCTGACGGTCACTTTGATGGGATCCTGTACGACACGTACCCACTCTCG
GAGGAGACCTGGCACACACACCAGTTCAACTTCATCAAGAACCACGCCTTTCGCCTGCTG
AAGCCGGGGGGCGTCCTCACCTACTGCAACCTCACCTCCTGGGGGGAGCTGATGAAGTCC
AAGTACTCAGACATCACCATCATGTTTGAGGAGACGCAGGTGCCCGCGCTGCTGGAGGCC
GGCTTCCGGAGGGAGAACATCCGTACGGAGGTGATGGCGCTGGTCCCACCGGCCGACTGC
CGCTACTACGCCTTCCCACAGATGATCACGCCCCTGGTGACCAAAGGCTGA
|
Protein Properties |
Number of Residues
| 236 |
Molecular Weight
| 26317.925 |
Theoretical pI
| 6.144 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Guanidinoacetate N-methyltransferase
MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYMHALAAAASSK
GGRVLEVGFGMAIAASKVQEAPIDEHWIIECNDGVFQRLRDWAPRQTHKVIPLKGLWEDV
APTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKS
KYSDITIMFEETQVPALLEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKG
|
External Links |
GenBank ID Protein
| 3342733 |
UniProtKB/Swiss-Prot ID
| Q14353 |
UniProtKB/Swiss-Prot Entry Name
| GAMT_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AC005329 |
GeneCard ID
| GAMT |
GenAtlas ID
| GAMT |
HGNC ID
| HGNC:4136 |
References |
General References
| Not Available |