400 CDBP00399 Diphthine synthase Q9H2P9 DPH5_HUMAN true false Enzyme Homo_sapiens DPH5 285 31651.17 5.307 Involved in methyltransferase activity S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis (By similarity). NM_001077394.1 117190326 DPH5 1 1p21.2 DPH5 HGNC:24270 true hsa:51611 NP_001070862.1:NM_001077394.1;NP_001070863.1:NM_001077395.1;NP_057042.2:NM_015958.2 2020-06-12T23:06:49Z 2020-07-28T02:25:19Z 0 0 0