| Identification |
|---|
| HMDB Protein ID
| CDBP00390 |
| Secondary Accession Numbers
| Not Available |
| Name
| Malonyl-CoA-acyl carrier protein transacylase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- MCT
- Mitochondrial malonyltransferase
- [Acyl-carrier-protein] malonyltransferase
- Mitochondrial malonyl CoA:ACP acyltransferase
|
| Gene Name
| MCAT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transferase activity |
| Specific Function
| Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias.
|
| GO Classification
|
| Biological Process |
| fatty acid biosynthetic process |
| Cellular Component |
| mitochondrion |
| Function |
| transferase activity |
| binding |
| catalytic activity |
| Molecular Function |
| [acyl-carrier-protein] S-malonyltransferase activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| 22q13.31 |
| SNPs
| MCAT |
| Gene Sequence
|
>1173 bp
ATGAGCGTCCGGGTCGCACGGGTAGCGTGGGTCAGGGGCTTGGGCGCCAGCTACCGCCGC
GGCGCCTCGAGCTTCCCGGTGCCTCCGCCGGGCGCCCAGGGTGTAGCGGAGCTGCTGCGA
GATGCGACCGGGGCGGAGGAGGAGGCGCCCTGGGCGGCGACGGAGCGGCGAATGCCGGGC
CAGTGCTCCGTGCTGCTCTTCCCGGGCCAGGGCAGCCAGGTGGTGGGCATGGGCCGCGGT
CTGCTCAACTACCCGCGCGTCCGCGAACTCTACGCCGCCGCCCGCCGCGTGCTGGGCTAC
GACCTGCTGGAACTGAGCCTGCACGGGCCGCAGGAGACCCTGGACCGCACCGTGCACTGT
CAGCCCGCGATCTTCGTGGCATCGCTGGCCGCTGTCGAGAAACTACATCACCTGCAGCCC
TCGGTGATTGAGAACTGTGTTGCTGCTGCTGGATTCAGTGTGGGAGAGTTTGCAGCCCTA
GTGTTTGCCGGAGCCATGGAATTTGCTGAAGGTTTGTATGCAGTGAAAATCCGAGCTGAG
GCCATGCAGGAAGCTTCAGAAGCTGTCCCCAGTGGGATGCTGTCTGTCCTCGGCCAGCCT
CAGTCCAAGTTCAACTTCGCCTGTTTGGAAGCCCGGGAACACTGCAAGTCTTTAGGCATA
GAGAACCCCGTATGTGAAGTGTCCAACTACCTCTTTCCAGATTGCAGGGTGATTTCAGGA
CACCAAGAGGCTCTACGGTTTCTCCAGAAGAATTCCTCTAAGTTTCATTTCAGACGCACC
AGGATGTTGCCGGTTAGTGGCGCATTCCACACCCGCCTCATGGAGCCAGCCGTGGAGCCC
CTGACGCAAGCTTTAAAGGCAGTCGACATTAAGAAGCCTCTGGTTTCTGTCTACTCCAAC
GTCCACGCGCATAGATACAGGCATCCCGGGCACATCCACAAGCTGCTGGCCCAGCAGCTG
GTCTCCCCAGTGAAGTGGGAGCAGACGATGCATGCCATATACGAAAGGAAAAAGGGCAGG
GGGTTCCCCCAAACTTTCGAAGTAGGCCCTGGCAGGCAGCTGGGAGCCATCCTGAAGAGC
TGTAACATGCAGGCCTGGAAGTCCTACAGCGCCGTGGATGTGCTGCAGACCCTCGAACAT
GTGGACCTGGACCCTCAGGAGCCCCCGAGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 390 |
| Molecular Weight
| 19175.775 |
| Theoretical pI
| 6.169 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG
QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC
QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAE
AMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISG
HQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSN
VHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKS
CNMQAWKSYSAVDVLQTLEHVDLDPQEPPR
|
| External Links |
|---|
| GenBank ID Protein
| 8574364 |
| UniProtKB/Swiss-Prot ID
| Q8IVS2 |
| UniProtKB/Swiss-Prot Entry Name
| FABD_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL359401 |
| GeneCard ID
| MCAT |
| GenAtlas ID
| MCAT |
| HGNC ID
| HGNC:29622 |
| References |
|---|
| General References
| Not Available |