379 CDBP00378 Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN true false Enzyme Homo_sapiens AKR1C1 323 36788.02 7.891 Involved in oxidoreductase activity Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. 1MRQ;3C3U;3GUG;3NTY M86609 AKR1C1 10 10p15-p14 AKR1C1 HGNC:384 true hsa:1645 NP_001344.2:NM_001353.5 Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain. Monomer 2020-06-12T23:06:49Z 2020-07-28T02:25:17Z 0 0 0