Identification |
HMDB Protein ID
| CDBP00361 |
Secondary Accession Numbers
| Not Available |
Name
| ADP-dependent glucokinase |
Description
| Not Available |
Synonyms
|
- ADP-GK
- ADPGK
- RbBP-35
|
Gene Name
| ADPGK |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in phosphotransferase activity, alcohol group as acceptor |
Specific Function
| Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity).
|
GO Classification
|
Biological Process |
glycolysis |
Cellular Component |
extracellular region |
Function |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
phosphotransferase activity, alcohol group as acceptor |
Molecular Function |
metal ion binding |
ADP-specific glucokinase activity |
Process |
carbohydrate metabolic process |
metabolic process |
primary metabolic process |
|
Cellular Location
|
- Secreted (Potential)
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Glycolysis / Gluconeogenesis | Not Available | |
|
Gene Properties |
Chromosome Location
| 15 |
Locus
| 15q24.1 |
SNPs
| ADPGK |
Gene Sequence
|
>1494 bp
ATGGCGCTGTGGCGCGGCTCCGCGTACGCGGGCTTCCTGGCGCTGGCCGTGGGCTGCGTC
TTCCTGCTGGAGCCAGAGCTGCCAGGCTCGGCGCTGCGCTCTCTCTGGAGCTCGCTGTGT
CTGGGGCCCGCGCCTGCGCCCCCGGGACCCGTCTCCCCCGAGGGCCGGTTGGCGGCAGCC
TGGGACGCGCTTATCGTGCGGCCAGTCCGGCGCTGGCGCCGCGTGGCAGTGGGAGTCAAT
GCATGTGTTGATGTGGTGCTCTCAGGGGTGAAGCTCTTGCAGGCACTTGGCCTTAGTCCT
GGGAATGGGAAAGATCACAGCATTCTGCATTCAAGGAATGATCTGGAAGAAGCCTTCATT
CACTTCATGGGGAAGGGAGCAGCTGCTGAGCGCTTCTTCAGTGATAAGGAAACTTTTCAC
GACATTGCCCAGGTTGCGTCAGAGTTCCCAGGAGCCCAGCACTATGTAGGAGGAAATGCA
GCTTTAATTGGACAGAAATTTGCAGCCAACTCAGATTTAAAGGTTCTTCTTTGCGGTCCA
GTTGGTCCAAAGCTACATGAGCTTCTTGATGACAATGTCTTTGTTCCACCAGAGTCATTG
CAGGAAGTGGATGAGTTCCACCTCATTTTAGAGTATCAAGCAGGGGAGGAGTGGGGCCAG
TTAAAAGCTCCCCATGCCAACCGATTCATCTTCTCTCACGACCTCTCCAACGGGGCCATG
AATATGCTGGAGGTGTTTGTGTCTAGCCTGGAGGAGTTTCAGCCAGACCTGGTGGTCCTC
TCTGGATTGCACATGATGGAGGGACAAAGCAAGGAGCTCCAGAGGAAGAGACTCTTGGAG
GTTGTAACCTCCATTTCTGACATCCCCACTGGTATTCCAGTTCACCTAGAGCTGGCCAGT
ATGACTAACAGGGAGCTCATGAGCAGCATTGTCCATCAGCAGGTCTTTCCCGCGGTGACT
TCCCTTGGGCTGAATGAACAGGAGCTGTTATTTCTCACCCAGTCAGCCTCTGGACCTCAC
TCTTCTCTCTCTTCCTGGAACGGTGTTCCTGATGTGGGCATGGTCAGTGACATCCTCTTC
TGGATCTTGAAAGAACATGGGAGGAGTAAAAGCAGAGCCTCGGATCTCACCAGGATCCAT
TTCCACACGCTGGTCTACCACATCCTGGCAACTGTGGATGGACACTGGGCCAACCAGCTG
GCAGCCGTGGCTGCAGGAGCTCGTGTGGCTGGGACACAGGCCTGCGCCACAGAAACCATA
GACACCAGCCGAGTGTCTCTGAGGGCACCCCAAGAGTTCATGACTTCCCATTCGGAGGCA
GGCTCCAGGATTGTATTAAACCCAAACAAGCCAGTAGTAGAATGGCACAGAGAGGGAATA
TCCTTCCACTTCACACCAGTATTGGTGTGTAAAGACCCCATTCGAACTGTAGGCCTTGGA
GATGCCATTTCAGCCGAAGGACTCTTCTATTCGGAAGTACACCCTCACTATTAG
|
Protein Properties |
Number of Residues
| 497 |
Molecular Weight
| 53960.185 |
Theoretical pI
| 6.207 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>ADP-dependent glucokinase
MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA
WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI
HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP
VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM
NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS
MTNRELMSSIVHQQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILF
WILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETI
DTSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLG
DAISAEGLFYSEVHPHY
|
External Links |
GenBank ID Protein
| 13543940 |
UniProtKB/Swiss-Prot ID
| Q9BRR6 |
UniProtKB/Swiss-Prot Entry Name
| ADPGK_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC006112 |
GeneCard ID
| ADPGK |
GenAtlas ID
| ADPGK |
HGNC ID
| HGNC:25250 |
References |
General References
| Not Available |