Identification
HMDB Protein ID CDBP00361
Secondary Accession Numbers Not Available
Name ADP-dependent glucokinase
Description Not Available
Synonyms
  1. ADP-GK
  2. ADPGK
  3. RbBP-35
Gene Name ADPGK
Protein Type Enzyme
Biological Properties
General Function Involved in phosphotransferase activity, alcohol group as acceptor
Specific Function Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity).
GO Classification
Biological Process
glycolysis
Cellular Component
extracellular region
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
Molecular Function
metal ion binding
ADP-specific glucokinase activity
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Cellular Location
  1. Secreted (Potential)
Pathways
Gene Properties
Chromosome Location 15
Locus 15q24.1
SNPs ADPGK
Gene Sequence
>1494 bp
ATGGCGCTGTGGCGCGGCTCCGCGTACGCGGGCTTCCTGGCGCTGGCCGTGGGCTGCGTC
TTCCTGCTGGAGCCAGAGCTGCCAGGCTCGGCGCTGCGCTCTCTCTGGAGCTCGCTGTGT
CTGGGGCCCGCGCCTGCGCCCCCGGGACCCGTCTCCCCCGAGGGCCGGTTGGCGGCAGCC
TGGGACGCGCTTATCGTGCGGCCAGTCCGGCGCTGGCGCCGCGTGGCAGTGGGAGTCAAT
GCATGTGTTGATGTGGTGCTCTCAGGGGTGAAGCTCTTGCAGGCACTTGGCCTTAGTCCT
GGGAATGGGAAAGATCACAGCATTCTGCATTCAAGGAATGATCTGGAAGAAGCCTTCATT
CACTTCATGGGGAAGGGAGCAGCTGCTGAGCGCTTCTTCAGTGATAAGGAAACTTTTCAC
GACATTGCCCAGGTTGCGTCAGAGTTCCCAGGAGCCCAGCACTATGTAGGAGGAAATGCA
GCTTTAATTGGACAGAAATTTGCAGCCAACTCAGATTTAAAGGTTCTTCTTTGCGGTCCA
GTTGGTCCAAAGCTACATGAGCTTCTTGATGACAATGTCTTTGTTCCACCAGAGTCATTG
CAGGAAGTGGATGAGTTCCACCTCATTTTAGAGTATCAAGCAGGGGAGGAGTGGGGCCAG
TTAAAAGCTCCCCATGCCAACCGATTCATCTTCTCTCACGACCTCTCCAACGGGGCCATG
AATATGCTGGAGGTGTTTGTGTCTAGCCTGGAGGAGTTTCAGCCAGACCTGGTGGTCCTC
TCTGGATTGCACATGATGGAGGGACAAAGCAAGGAGCTCCAGAGGAAGAGACTCTTGGAG
GTTGTAACCTCCATTTCTGACATCCCCACTGGTATTCCAGTTCACCTAGAGCTGGCCAGT
ATGACTAACAGGGAGCTCATGAGCAGCATTGTCCATCAGCAGGTCTTTCCCGCGGTGACT
TCCCTTGGGCTGAATGAACAGGAGCTGTTATTTCTCACCCAGTCAGCCTCTGGACCTCAC
TCTTCTCTCTCTTCCTGGAACGGTGTTCCTGATGTGGGCATGGTCAGTGACATCCTCTTC
TGGATCTTGAAAGAACATGGGAGGAGTAAAAGCAGAGCCTCGGATCTCACCAGGATCCAT
TTCCACACGCTGGTCTACCACATCCTGGCAACTGTGGATGGACACTGGGCCAACCAGCTG
GCAGCCGTGGCTGCAGGAGCTCGTGTGGCTGGGACACAGGCCTGCGCCACAGAAACCATA
GACACCAGCCGAGTGTCTCTGAGGGCACCCCAAGAGTTCATGACTTCCCATTCGGAGGCA
GGCTCCAGGATTGTATTAAACCCAAACAAGCCAGTAGTAGAATGGCACAGAGAGGGAATA
TCCTTCCACTTCACACCAGTATTGGTGTGTAAAGACCCCATTCGAACTGTAGGCCTTGGA
GATGCCATTTCAGCCGAAGGACTCTTCTATTCGGAAGTACACCCTCACTATTAG
Protein Properties
Number of Residues 497
Molecular Weight 53960.185
Theoretical pI 6.207
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>ADP-dependent glucokinase
MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA
WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI
HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP
VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM
NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS
MTNRELMSSIVHQQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILF
WILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETI
DTSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLG
DAISAEGLFYSEVHPHY
GenBank ID Protein 13543940
UniProtKB/Swiss-Prot ID Q9BRR6
UniProtKB/Swiss-Prot Entry Name ADPGK_HUMAN
PDB IDs Not Available
GenBank Gene ID BC006112
GeneCard ID ADPGK
GenAtlas ID ADPGK
HGNC ID HGNC:25250
References
General References Not Available