280 CDBP00279 Eosinophil peroxidase P11678 PERE_HUMAN true false Enzyme Homo_sapiens EPX 715 81039.5 10.285 Involved in peroxidase activity Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. DQ054598 66268791 EPX 17 17q23.1 EPX HGNC:3423 true hsa:8288 NP_000493.1:NM_000502.4 calcium ion per heterodimer;heme B (iron-protoporphyrin IX) covalently through ester linkages to hydroxylated methyl groups formed auto-catalytically with hydrogen peroxide at the heme C-1 and C-5 positions. The ester linkage to Asp-232 was observed in 30% of the chains Tetramer of two light chains and two heavy chains 2020-06-12T23:06:48Z 2020-07-28T02:25:07Z 0 1 0