Identification |
HMDB Protein ID
| CDBP00263 |
Secondary Accession Numbers
| Not Available |
Name
| Phosphoglycerate mutase 1 |
Description
| Not Available |
Synonyms
|
- BPG-dependent PGAM 1
- PGAM-B
- Phosphoglycerate mutase isozyme B
|
Gene Name
| PGAM1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
|
GO Classification
|
Biological Process |
small molecule metabolic process |
regulation of glycolysis |
glycolysis |
gluconeogenesis |
regulation of pentose-phosphate shunt |
respiratory burst |
Cellular Component |
cytosol |
Function |
catalytic activity |
isomerase activity |
intramolecular transferase activity |
intramolecular transferase activity, phosphotransferases |
Molecular Function |
bisphosphoglycerate 2-phosphatase activity |
bisphosphoglycerate mutase activity |
phosphoglycerate mutase activity |
Process |
metabolic process |
small molecule metabolic process |
alcohol metabolic process |
monosaccharide metabolic process |
hexose metabolic process |
glucose metabolic process |
glucose catabolic process |
glycolysis |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Glycolysis / Gluconeogenesis | Not Available | | Glycine, serine and threonine metabolism | Not Available | | Glycolysis | | | Glycogenosis, Type VII. Tarui disease | | Not Available | Fanconi-bickel syndrome | | Not Available |
|
Gene Properties |
Chromosome Location
| 10 |
Locus
| 10q25.3 |
SNPs
| PGAM1 |
Gene Sequence
|
>765 bp
ATGGCCGCCTACAAACTGGTGCTGATCCGGCACGGCGAGAGCGCATGGAACCTGGAGAAC
CGCTTCAGCGGCTGGTACGACGCCGACCTGAGCCCGGCGGGCCACGAGGAGGCGAAGCGC
GGCGGGCAGGCGCTACGAGATGCTGGCTATGAGTTTGACATCTGCTTCACCTCAGTGCAG
AAGAGAGCGATCCGGACCCTCTGGACAGTGCTAGATGCCATTGATCAGATGTGGCTGCCA
GTGGTGAGGACTTGGCGCCTCAATGAGCGGCACTATGGGGGTCTAACCGGTCTCAATAAA
GCAGAAACTGCTGCAAAGCATGGTGAGGCCCAGGTGAAGATCTGGAGGCGCTCCTATGAT
GTCCCACCACCTCCGATGGAGCCCGACCATCCTTTCTACAGCAACATCAGTAAGGATCGC
AGGTATGCAGACCTCACAGAAGATCAGCTACCCTCCTGTGAGAGTCTGAAGGATACTATT
GCCAGAGCTCTGCCCTTCTGGAATGAAGAAATAGTTCCCCAGATCAAGGAGGGGAAACGT
GTACTGATTGCAGCCCATGGCAACAGCCTCCGGGGCATTGTCAAGCATCTGGAGGGTCTC
TCTGAAGAGGCTATCATGGAGCTGAACCTGCCGACTGGTATTCCCATTGTCTATGAATTG
GACAAGAACTTGAAGCCTATCAAGCCCATGCAGTTTCTGGGGGATGAAGAGACGGTGCGC
AAAGCCATGGAAGCTGTGGCTGCCCAGGGCAAGGCCAAGAAGTGA
|
Protein Properties |
Number of Residues
| 254 |
Molecular Weight
| 28803.675 |
Theoretical pI
| 7.182 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Phosphoglycerate mutase 1
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
KAMEAVAAQGKAKK
|
External Links |
GenBank ID Protein
| 9956014 |
UniProtKB/Swiss-Prot ID
| P18669 |
UniProtKB/Swiss-Prot Entry Name
| PGAM1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AY007118 |
GeneCard ID
| PGAM1 |
GenAtlas ID
| PGAM1 |
HGNC ID
| HGNC:8888 |
References |
General References
| Not Available |