194 CDBP00193 Heme oxygenase 1 P09601 HMOX1_HUMAN true false Enzyme Homo_sapiens HMOX1 288 32818.345 8.257 Involved in heme oxygenase (decyclizing) activity Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. 1N3U;1N45;1NI6;1OYK;1OYL;1OZE;1OZL;1OZR;1OZW;1S13;1S8C;1T5P;1TWN;1TWR;1XJZ;1XK0;1XK1;1XK2;1XK3;3CZY;3HOK;3K4F;3TGM X06985 35173 HMOX1 22 22q13.1 HMOX1 HGNC:5013 true hsa:3162 HS02027-MONOMER NP_002124.1:NM_002133.2 Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). 2020-06-12T23:06:48Z 2020-07-28T02:24:59Z 0 1 1