Cannabis Compound Database: Showing Protein Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (CDBP00188)

Identification Biological properties Gene properties Protein properties External links References XML Show 7 compounds

Identification

HMDB Protein ID

CDBP00188

Secondary Accession Numbers

Not Available

Name

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Description

Not Available

Synonyms

Ip
Iron-sulfur subunit of complex II

Gene Name

SDHB

Protein Type

Enzyme

Biological Properties

General Function

Involved in electron carrier activity

Specific Function

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

GO Classification

Biological Process
small molecule metabolic process
tricarboxylic acid cycle
succinate metabolic process
respiratory electron transport chain
Cellular Component
mitochondrial respiratory chain complex II
Function
oxidoreductase activity
binding
catalytic activity
electron carrier activity
metal cluster binding
iron-sulfur cluster binding
Molecular Function
electron carrier activity
metal ion binding
2 iron, 2 sulfur cluster binding
4 iron, 4 sulfur cluster binding
3 iron, 4 sulfur cluster binding
succinate dehydrogenase (ubiquinone) activity
ubiquinone binding
Process
metabolic process
cellular metabolic process
oxidation reduction
cofactor metabolic process
coenzyme metabolic process
acetyl-coa metabolic process
acetyl-coa catabolic process
tricarboxylic acid cycle

Cellular Location

Peripheral membrane protein
Mitochondrion inner membrane
Matrix side

Pathways

Name	SMPDB/Pathwhiz	KEGG
tricarboxylic acid cycle	Not Available	Not Available
Citrate cycle (TCA cycle)	Not Available
Oxidative phosphorylation	Not Available
Alzheimer's disease	Not Available
Parkinson's disease	Not Available

Gene Properties

Chromosome Location

Locus

1p36.1-p35

SNPs

SDHB

Gene Sequence

>843 bp
ATGGCGGCGGTGGTCGCACTCTCCTTGAGGCGCCGGTTGCCGGCCACAACCCTTGGCGGA
GCCTGCCTGCAGGCCTCCCGAGGAGCCCAGACAGCTGCAGCCACAGCTCCCCGTATCAAG
AAATTTGCCATCTATCGATGGGACCCAGACAAGGCTGGAGACAAACCTCATATGCAGACT
TATGAAGTTGACCTTAATAAATGTGGCCCCATGGTATTGGATGCTTTAATCAAGATTAAG
AATGAAGTTGACTCTACTTTGACCTTCCGAAGATCATGCAGAGAAGGCATCTGTGGCTCT
TGTGCAATGAACATCAATGGAGGCAACACTCTAGCTTGCACCCGAAGGATTGACACCAAC
CTCAATAAGGTCTCAAAAATCTACCCTCTTCCACACATGTATGTGATAAAGGATCTTGTT
CCCGATTTGAGCAACTTCTATGCACAGTACAAATCCATTGAGCCTTATTTGAAGAAGAAG
GATGAATCTCAGGAAGGCAAGCAGCAGTATCTGCAGTCCATAGAAGAGCGTGAGAAACTG
GACGGGCTCTACGAGTGCATTCTCTGTGCCTGCTGTAGCACCAGCTGCCCCAGCTACTGG
TGGAACGGAGACAAATATCTGGGGCCTGCAGTTCTTATGCAGGCCTATCGCTGGATGATT
GACTCCAGAGATGACTTCACAGAGGAGCGCCTGGCCAAGCTGCAGGACCCATTCTCTCTA
TACCGCTGCCACACCATCATGAACTGCACAAGGACCTGTCCTAAGGGTCTGAATCCAGGG
AAAGCTATTGCAGAGATCAAGAAAATGATGGCAACCTATAAGGAGAAGAAAGCTTCAGTT
TAA

Protein Properties

Number of Residues

280

Molecular Weight

31629.365

Theoretical pI

8.76

Pfam Domain Function

Fer2_3 (PF13085 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQT
YEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTN
LNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKL
DGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSL
YRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV

External Links

GenBank ID Protein

189065269

UniProtKB/Swiss-Prot ID

P21912

UniProtKB/Swiss-Prot Entry Name

DHSB_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AK312056

GeneCard ID