<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">151</id>
  <cancdbp-id>CDBP00150</cancdbp-id>
  <name>Dimethylaniline monooxygenase [N-oxide-forming] 2</name>
  <uniprot-id>Q99518</uniprot-id>
  <uniprot-name>FMO2_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>FMO2</gene-name>
  <num-residues type="integer">535</num-residues>
  <molecular-weight type="decimal">53643.29</molecular-weight>
  <theoretical-pi type="decimal">7.203</theoretical-pi>
  <general-function>Involved in flavin-containing monooxygenase activity</general-function>
  <specific-function>Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids></pdb-ids>
  <genbank-gene-id>BT006979</genbank-gene-id>
  <genbank-protein-id>4503757</genbank-protein-id>
  <genecard-id>FMO2</genecard-id>
  <chromosome-location>1</chromosome-location>
  <locus>1q24.3</locus>
  <geneatlas-id>FMO2</geneatlas-id>
  <hgnc-id>HGNC:3770</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:2327</kegg-id>
  <meta-cyc-id></meta-cyc-id>
  <ncbi-sequence-ids>NP_001451.1:NM_001460.2</ncbi-sequence-ids>
  <tissue-specificity>Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
</tissue-specificity>
  <cofactor>FAD;Magnesium</cofactor>
  <subunit></subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:47Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:24:56Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">0</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

