Showing Protein Low molecular weight phosphotyrosine protein phosphatase (CDBP00092)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP00092
Secondary Accession Numbers Not Available
Name Low molecular weight phosphotyrosine protein phosphatase
Description Not Available
Synonyms
  1. Adipocyte acid phosphatase
  2. LMW-PTP
  3. LMW-PTPase
  4. Low molecular weight cytosolic acid phosphatase
  5. Red cell acid phosphatase 1
Gene Name ACP1
Protein Type Enzyme
Biological Properties
General Function Involved in acid phosphatase activity
Specific Function Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
GO Classification
Biological Process
synaptic transmission
Cellular Component
cytoplasm
nucleus
internal side of plasma membrane
Component
cell part
intracellular part
cytoplasm
Function
acid phosphatase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
Molecular Function
acid phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
Process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation
protein amino acid dephosphorylation
metabolic process
cellular metabolic process
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 2
Locus 2p25
SNPs ACP1
Gene Sequence 
>477 bp
ATGGCGGAACAGGCTACCAAGTCCGTGCTGTTTGTGTGTCTGGGTAACATTTGTCGATCA
CCCATTGCAGAAGCAGTTTTCAGGAAACTTGTAACCGATCAAAACATCTCAGAGAATTGG
AGGGTAGACAGCGCGGCAACTTCCGGGTATGAGATAGGGAACCCCCCTGACTACCGAGGG
CAGAGCTGCATGAAGAGGCACGGCATTCCCATGAGCCACGTTGCCCGGCAGATTACCAAA
GAAGATTTTGCCACATTTGATTATATACTATGTATGGATGAAAGCAATCTGAGAGATTTG
AATAGAAAAAGTAATCAAGTTAAAACCTGCAAAGCTAAAATTGAACTACTTGGGAGCTAT
GATCCACAAAAACAACTTATTATTGAAGATCCCTATTATGGGAATGACTCTGACTTTGAG
ACGGTGTACCAGCAGTGTGTCAGGTGCTGCAGAGCGTTCTTGGAGAAGGCCCACTGA
Protein Properties
Number of Residues 158
Molecular Weight 18042.315
Theoretical pI 6.737
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Low molecular weight phosphotyrosine protein phosphatase
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P24666
UniProtKB/Swiss-Prot Entry Name PPAC_HUMAN
PDB IDs
GenBank Gene ID M83653
GeneCard ID ACP1
GenAtlas ID ACP1
HGNC ID HGNC:122
References
General References Not Available