| Identification |
|---|
| HMDB Protein ID
| CDBP00092 |
| Secondary Accession Numbers
| Not Available |
| Name
| Low molecular weight phosphotyrosine protein phosphatase |
| Description
| Not Available |
| Synonyms
|
- Adipocyte acid phosphatase
- LMW-PTP
- LMW-PTPase
- Low molecular weight cytosolic acid phosphatase
- Red cell acid phosphatase 1
|
| Gene Name
| ACP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acid phosphatase activity |
| Specific Function
| Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
|
| GO Classification
|
| Biological Process |
| synaptic transmission |
| Cellular Component |
| cytoplasm |
| nucleus |
| internal side of plasma membrane |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| acid phosphatase activity |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| non-membrane spanning protein tyrosine phosphatase activity |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| Molecular Function |
| acid phosphatase activity |
| non-membrane spanning protein tyrosine phosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Adherens junction | Not Available |  | | Riboflavin Metabolism |    |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| 2p25 |
| SNPs
| ACP1 |
| Gene Sequence
|
>477 bp
ATGGCGGAACAGGCTACCAAGTCCGTGCTGTTTGTGTGTCTGGGTAACATTTGTCGATCA
CCCATTGCAGAAGCAGTTTTCAGGAAACTTGTAACCGATCAAAACATCTCAGAGAATTGG
AGGGTAGACAGCGCGGCAACTTCCGGGTATGAGATAGGGAACCCCCCTGACTACCGAGGG
CAGAGCTGCATGAAGAGGCACGGCATTCCCATGAGCCACGTTGCCCGGCAGATTACCAAA
GAAGATTTTGCCACATTTGATTATATACTATGTATGGATGAAAGCAATCTGAGAGATTTG
AATAGAAAAAGTAATCAAGTTAAAACCTGCAAAGCTAAAATTGAACTACTTGGGAGCTAT
GATCCACAAAAACAACTTATTATTGAAGATCCCTATTATGGGAATGACTCTGACTTTGAG
ACGGTGTACCAGCAGTGTGTCAGGTGCTGCAGAGCGTTCTTGGAGAAGGCCCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 158 |
| Molecular Weight
| 18042.315 |
| Theoretical pI
| 6.737 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Low molecular weight phosphotyrosine protein phosphatase
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P24666 |
| UniProtKB/Swiss-Prot Entry Name
| PPAC_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M83653 |
| GeneCard ID
| ACP1 |
| GenAtlas ID
| ACP1 |
| HGNC ID
| HGNC:122 |
| References |
|---|
| General References
| Not Available |