| Identification |
|---|
| HMDB Protein ID
| CDBP00060 |
| Secondary Accession Numbers
| Not Available |
| Name
| Group XIIB secretory phospholipase A2-like protein |
| Description
| Not Available |
| Synonyms
|
- GXIIB
- GXIII sPLA2-like
- Group XIII secretory phospholipase A2-like protein
- sPLA2-GXIIB
|
| Gene Name
| PLA2G12B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phospholipase A2 activity |
| Specific Function
| Not known; does not seem to have catalytic activity.
|
| GO Classification
|
| Biological Process |
| lipid catabolic process |
| Cellular Component |
| extracellular region |
| Component |
| extracellular region |
| Function |
| carboxylesterase activity |
| phospholipase a2 activity |
| ion binding |
| cation binding |
| metal ion binding |
| hydrolase activity, acting on ester bonds |
| binding |
| catalytic activity |
| hydrolase activity |
| calcium ion binding |
| Molecular Function |
| phospholipase A2 activity |
| calcium ion binding |
| Process |
| metabolic process |
| primary metabolic process |
| lipid metabolic process |
| lipid catabolic process |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycerophospholipid metabolism | Not Available |  | | Ether lipid metabolism | Not Available |  | | Linoleic acid metabolism | Not Available |  | | alpha-Linolenic acid metabolism | Not Available |  | | Vascular smooth muscle contraction | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| PLA2G12B |
| Gene Sequence
|
>588 bp
ATGAAGCTGGCCAGTGGCTTCTTGGTTTTGTGGCTCAGCCTTGGGGGTGGCCTGGCTCAG
AGCGACACGAGCCCTGACACGGAGGAGTCCTATTCAGACTGGGGCCTTCGGCACCTCCGG
GGAAGCTTTGAATCCGTCAATAGCTACTTCGATTCTTTTCTGGAGCTGCTGGGAGGGAAG
AATGGAGTCTGTCAGTACAGGTGCCGATATGGAAAGGCACCAATGCCCAGACCTGGCTAC
AAGCCCCAAGAGCCCAATGGCTGCGGCTCCTATTTCCTGGGTCTCAAGGTACCAGAAAGT
ATGGACTTGGGCATTCCAGCAATGACAAAGTGCTGCAACCAGCTGGATGTCTGTTATGAC
ACTTGCGGTGCCAACAAATATCGCTGTGATGCAAAATTCCGATGGTGTCTCCACTCGATC
TGCTCTGACCTTAAGCGGAGTCTGGGCTTTGTCTCCAAAGTGGAAGCAGCCTGTGATTCC
CTGGTTGACACTGTGTTCAACACCGTGTGGACCTTGGGCTGCCGCCCCTTTATGAATAGT
CAGCGGGCAGCTTGCATCTGTGCAGAGGAGGAGAAGGAAGAGTTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 195 |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Group XIIB secretory phospholipase A2-like protein
MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGK
NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD
TCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNS
QRAACICAEEEKEEL
|
| External Links |
|---|
| GenBank ID Protein
| 15824793 |
| UniProtKB/Swiss-Prot ID
| Q9BX93 |
| UniProtKB/Swiss-Prot Entry Name
| PG12B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF339053 |
| GeneCard ID
| PLA2G12B |
| GenAtlas ID
| PLA2G12B |
| HGNC ID
| HGNC:18555 |
| References |
|---|
| General References
| Not Available |