54 CDBP00053 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial P10515 ODP2_HUMAN true false Enzyme Homo_sapiens DLAT 647 68996.03 7.835 Involved in acyltransferase activity The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. 1FYC;1Y8N;1Y8O;1Y8P;2DNE;2PNR;2Q8I;3B8K;3CRK;3CRL AK223596 62898924 DLAT 11 11q23.1 DLAT HGNC:2896 true hsa:1737 HS07688-MONOMER NP_001922.2:NM_001931.4 lipoyl cofactors covalently Part of the multimeric pyruvate dehydrogenase complex that contains multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (DLAT, E2) and lipoamide dehydrogenase (DLD, E3). These subunits are bound to an inner core composed of about 48 DLAT and 12 PDHX molecules. Interacts with PDK2 and PDK3 2020-06-12T23:06:47Z 2020-06-12T23:06:47Z 0 0 0