49 CDBP00048 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial P29803 ODPAT_HUMAN true false Enzyme Homo_sapiens PDHA2 388 42932.855 8.46 Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. AK313872 PDHA2 4 4q22-q23 PDHA2 HGNC:8807 true hsa:5161 NP_005381.1:NM_005390.4 Testis. Expressed in postmeiotic spermatogenic cells. Thiamine pyrophosphate Heterotetramer of two PDHA2 and two PDHB subunits. The heterotetramer interacts with DLAT, and is part of the multimeric pyruvate dehydrogenase complex that contains multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (DLAT, E2) and lipoamide dehydrogenase (DLD, E3). These subunits are bound to an inner core composed of about 48 DLAT and 12 PDHX molecules 2020-06-12T23:06:47Z 2020-06-12T23:06:47Z 0 0 0