Identification |
HMDB Protein ID
| CDBP00041 |
Secondary Accession Numbers
| Not Available |
Name
| Citrate synthase, mitochondrial |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| CS |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
cellular carbohydrate metabolic process |
citrate metabolic process |
tricarboxylic acid cycle |
oxaloacetate metabolic process |
carbohydrate metabolic process |
small molecule metabolic process |
Cellular Component |
mitochondrial matrix |
Function |
catalytic activity |
transferase activity |
transferase activity, transferring acyl groups |
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
citrate (si)-synthase activity |
Molecular Function |
citrate (Si)-synthase activity |
Process |
cellular metabolic process |
cofactor metabolic process |
coenzyme metabolic process |
acetyl-coa metabolic process |
acetyl-coa catabolic process |
tricarboxylic acid cycle |
metabolic process |
primary metabolic process |
carbohydrate metabolic process |
cellular carbohydrate metabolic process |
|
Cellular Location
|
- Mitochondrion matrix
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Citric Acid Cycle | | | Transfer of Acetyl Groups into Mitochondria | | Not Available | tricarboxylic acid cycle | Not Available | Not Available | Citrate cycle (TCA cycle) | Not Available | | Glyoxylate and dicarboxylate metabolism | Not Available | |
|
Gene Properties |
Chromosome Location
| 12 |
Locus
| 12q13.2 |
SNPs
| CS |
Gene Sequence
|
>1401 bp
ATGGCTTTACTTACTGCGGCCGCCCGGCTCTTGGGAACCAAGAATGCATCTTGTCTTGTT
CTTGCAGCCCGGCATGCTAGTGCTTCCTCCACGAATTTGAAAGACATATTGGCTGACCTG
ATACCTAAGGAGCAGGCCAGAATTAAGACTTTCAGGCAGCAACATGGCAAGACGGTGGTG
GGCCAAATCACTGTGGACATGATGTATGGTGGCATGAGAGGCATGAAGGGATTGGTGTAT
GAAACATCAGTTCTTGATCCTGATGAGGGCATCCGTTTCCGAGGCTTTAGTATCCCTGAA
TGCCAGAAACTGCTACCCAAGGCTAAGGGTGGGGAAGAACCCCTGCCTGAGGGCTTATTT
TGGCTGCTGGTAACTGGATGTATCCCAACAGAGGAACAGGTATCTTGGCTCTCAAAAGAG
TGGGCAAAGAGGGCAGCTCTGCCTTCCCATGTGGTCACCATGCTGGACAACTTTCCCACC
AATCTACACCCCATGTCTCAGCTGAGTGCAGCTGTTACAGCCCTCAACAGTGAAAGTAAC
TTTGCCCAAGCATATGCACGGGGTATCAGCCGAACCAAGTACTGGGAGTTGATTTATGAA
GATTCTGTGGATCTAATAGCAAAGCTACCTTGTGTTGCAGCAAAGATCTACCGAAATCTC
TACTGGGAAGGCAGCGGTATTGGGGCCATTGACTCTAACCTGGACTGGTCTCACAATTTC
ACCAACATGTTAGGCTATACTGATCATCAGTTCACTGAGCTCATGCGCCTGTACCTCACC
ATCCACAGTGACCATGAGGGTGGCAATGTAAGTGCCCATACCAGCCACTTGGTGGGCAGT
GCCCTTTCCGACCCTTACCTGTCCTTTGCAGCAGCCATGAACGGGCTGGCAGGGCCTCTC
CATGGACTGGCAAATCAGGAAGTGCTTGTCTGGCTAACACAGCTGCAGAAGGAAGTTGGC
AAAGATGTGTCAGATGAGAAGTTACGAGACTACATCTGGAACACACTCAACTCAGGACGG
GTTGTTCCAGGCTATGGCCATGCAGTACTAAGGAAGACTGATCCGCGATATACCTGTCAG
CGAGAGTTTGCTCTGAAACACCTGCCTAATGACCCCATGTTTAAGTTGGTTGCTCAGCTG
TACAAGATTGTGCCCAATGTCCTCTTAGAGCAGGGTAAAGCCAAGAATCCTTGGCCCAAT
GTAGATGCTCACAGTGGGGTGCTGCTCCAGTATTATGGCATGACGGAGATGAATTACTAC
ACGGTCCTGTTTGGGGTGTCACGAGCATTGGGTGTACTGGCACAGCTCATCTGGAGCCGA
GCCTTAGGCTTCCCTCTAGAAAGGCCCAAGTCCATGAGCACAGAGGGTCTGATGAAGTTT
GTGGACTCTAAGTCAGGGTAA
|
Protein Properties |
Number of Residues
| 466 |
Molecular Weight
| 51712.025 |
Theoretical pI
| 8.331 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Citrate synthase, mitochondrial
MALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVV
GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLF
WLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESN
FARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNF
TNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPL
HGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQ
REFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYY
TVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG
|
External Links |
GenBank ID Protein
| 3288815 |
UniProtKB/Swiss-Prot ID
| O75390 |
UniProtKB/Swiss-Prot Entry Name
| CISY_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF047042 |
GeneCard ID
| CS |
GenAtlas ID
| CS |
HGNC ID
| HGNC:2422 |
References |
General References
| Not Available |