Identification |
HMDB Protein ID
| CDBP00015 |
Secondary Accession Numbers
| Not Available |
Name
| Diamine acetyltransferase 2 |
Description
| Not Available |
Synonyms
|
- Polyamine N-acetyltransferase 2
- Spermidine/spermine N(1)-acetyltransferase 2
- Thialysine N-epsilon-acetyltransferase
|
Gene Name
| SAT2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in N-acetyltransferase activity |
Specific Function
| Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine.
|
GO Classification
|
Biological Process |
putrescine catabolic process |
Cellular Component |
cytoplasm |
Function |
n-acetyltransferase activity |
catalytic activity |
transferase activity |
transferase activity, transferring acyl groups |
transferase activity, transferring acyl groups other than amino-acyl groups |
acyltransferase activity |
acetyltransferase activity |
Molecular Function |
diamine N-acetyltransferase activity |
Process |
metabolic process |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | putrescine degradation | Not Available | Not Available |
|
Gene Properties |
Chromosome Location
| 17 |
Locus
| 17p13.1 |
SNPs
| SAT2 |
Gene Sequence
|
>513 bp
ATGGCTTCCGTGCGGATCCGAGAGGCCAAGGAGGGAGACTGTGGAGATATCCTGAGGCTG
ATTCGGGAGCTAGCCGAATTCGAAAAACTCTCGGATCAGGTGAAGATCAGTGAAGAAGCC
CTGAGAGCAGATGGCTTTGGAGACAATCCTTTCTATCACTGTTTGGTAGCAGAGATTCTT
CCAGCGCCCGGGAAGCTACTGGGGCCCTGCGTGGTGGGCTATGGGATATACTATTTCATC
TACAGTACATGGAAGGGACGCACCATTTATCTGGAGGATATCTATGTGATGCCAGAATAT
CGGGGTCAAGGGATTGGTTCCAAAATAATCAAAAAGGTGGCTGAGGTGGCCTTGGATAAG
GGCTGCTCCCAATTCCGCCTGGCCGTCCTGGACTGGAACCAGAGGGCCATGGACTTGTAC
AAGGCCCTAGGAGCCCAAGATCTGACGGAAGCTGAGGGCTGGCACTTCTTCTGCTTTCAA
GGAGAGGCAACGAGAAAGTTGGCAGGAAAGTGA
|
Protein Properties |
Number of Residues
| 170 |
Molecular Weight
| 19154.905 |
Theoretical pI
| 6.037 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Diamine acetyltransferase 2
MASVRIREAKEGDCGDILRLIRELAEFEKLSDQVKISEEALRADGFGDNPFYHCLVAEIL
PAPGKLLGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYRGQGIGSKIIKKVAEVALDK
GCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q96F10 |
UniProtKB/Swiss-Prot Entry Name
| SAT2_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF348524 |
GeneCard ID
| SAT2 |
GenAtlas ID
| SAT2 |
HGNC ID
| HGNC:23160 |
References |
General References
| Not Available |