Record Information |
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Version | 1.0 |
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Created at | 2020-04-27 16:42:58 UTC |
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Updated at | 2021-01-04 18:49:05 UTC |
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CannabisDB ID | CDB005660 |
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Secondary Accession Numbers | Not Available |
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Cannabis Compound Identification |
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Common Name | Butyroamide |
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Description | Butyroamide or Butyramide, also known as N-butanamide, belongs to the class of organic compounds known as fatty acid amides. These are carboxylic acid amide derivatives of fatty acids, that are formed from a fatty acid and an amine. Thus, butyramide is an amide of butyric acid. Butyramide is a crystalline solid at room temperature and is a nutty tasting compound. In contrast to butyric acid, it has no unpleasant or rancid smell. Butyramide can be found in cheeses. It has been shown to inhibit DNA synthesis in hepatoma cells and exhibit various growth inhibitory effects (PMID: 8476205 ). Butyramide is a constituent of cannabis smoke and is formed during the combustion of cannabis ( Ref:DOI ). |
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Structure | |
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Synonyms | Value | Source |
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Butanoic acid, amide | ChEBI | Butyramid | ChEBI | Butyrylamide | ChEBI | C3H7C(O)NH2 | ChEBI | N-Butanamide | ChEBI | N-Butylamide | ChEBI | N-Butyramide | ChEBI | N-C3H7C(O)NH2 | ChEBI | Butanoate, amide | Generator | Butanamide | HMDB | Butanimidic acid | HMDB |
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Chemical Formula | C4H9NO |
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Average Molecular Weight | 87.12 |
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Monoisotopic Molecular Weight | 87.0684 |
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IUPAC Name | butanamide |
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Traditional Name | butyramide |
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CAS Registry Number | 541-35-5 |
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SMILES | CCCC(O)=N |
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InChI Identifier | InChI=1S/C4H9NO/c1-2-3-4(5)6/h2-3H2,1H3,(H2,5,6) |
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InChI Key | DNSISZSEWVHGLH-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as fatty amides. These are carboxylic acid amide derivatives of fatty acids, that are formed from a fatty acid and an amine. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Fatty Acyls |
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Sub Class | Fatty amides |
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Direct Parent | Fatty amides |
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Alternative Parents | |
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Substituents | - Fatty amide
- Primary carboxylic acid amide
- Carboxamide group
- Carboxylic acid derivative
- Organic nitrogen compound
- Organic oxygen compound
- Organopnictogen compound
- Organic oxide
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Carbonyl group
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Ontology |
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Disposition | Route of exposure: Source: Biological location: |
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Role | Industrial application: Biological role: |
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Physical Properties |
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State | Solid |
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Experimental Properties | Property | Value | Reference |
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Melting Point | 115 - 116 °C | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | 163 mg/mL at 15 °C | Not Available | logP | -0.21 | Not Available |
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Predicted Properties | [] |
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Spectra |
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EI-MS/GC-MS | Type | Description | Splash Key | View |
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Predicted GC-MS | Butyroamide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-002f-9000000000-0a7a584657b22254012b | Spectrum | Predicted GC-MS | Butyroamide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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MS/MS | Type | Description | Splash Key | View |
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Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0079-9000000000-0eca6ad6056e9d99a12e | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-00di-9000000000-8d19ba5c849dd71e9f55 | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0006-9000000000-5d9ed5fdd5f033d01d27 | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-000i-9000000000-8eaa392a1fd75490f0db | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-000l-9000000000-3a0d3ac9af6de2874568 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9000000000-76f7e3debe07de7cbcf8 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0079-9000000000-64c195eaa3ea3d1f608a | 2021-09-24 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0006-9000000000-f36a9ace843ae2e9f73c | 2021-09-24 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0006-9000000000-00dbcef465bf69423cf0 | 2021-09-24 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-000i-9000000000-cac7a5f55f0489e13d41 | 2021-09-24 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-000f-9000000000-d2789779a3587ef6a706 | 2021-09-24 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9000000000-90726b17dc36e29c5299 | 2021-09-24 | View Spectrum |
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NMR | Not Available |
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Pathways |
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Pathways | Not Available |
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Protein Targets |
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Enzymes | Not Available |
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Transporters | Not Available |
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Metal Bindings | Not Available |
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Receptors | Not Available |
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Transcriptional Factors | Not Available |
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Concentrations Data |
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| Not Available |
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External Links |
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HMDB ID | HMDB0033870 |
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DrugBank ID | DB02121 |
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Phenol Explorer Compound ID | Not Available |
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FoodDB ID | FDB012058 |
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KNApSAcK ID | C00043175 |
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Chemspider ID | 10464 |
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KEGG Compound ID | Not Available |
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BioCyc ID | Not Available |
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BiGG ID | Not Available |
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Wikipedia Link | Butanamide |
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METLIN ID | Not Available |
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PubChem Compound | 10927 |
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PDB ID | BMD |
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ChEBI ID | 50724 |
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References |
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General References | - Lea MA, Xiao Q, Sadhukhan A, Sharma S, Newmark HL: Butyramide and monobutyrin: growth inhibitory and differentiating agents. Anticancer Res. 1993 Jan-Feb;13(1):145-9. [PubMed:8476205 ]
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